Horizon 2020 Funding Opportunities and How to Get Involved – Focus on the Health area

1. Horizon 2020Funding Opportunities and How to Get Involved – Focus on the Health area Aberdeen University14 November 2013 • Edward Ricketts edward.ricketts@bbsrc.ac.uk

2. UK Research Office • UKRO’s Mission: “To promote effective UK engagement in EU research, innovation and higher education activities” • The Office: • Is based in Brussels, was established in 1984 • Is sponsored by the seven UK Research Councils • Around 130 research organisations subscribe to UKRO

3. UKRO subscriber services • UKRO Portal: tailored news articles and clear and accessible web pages on the latest in EU funding • Enquiry service: individual support through your dedicated European Advisor • Annual briefing visits: bespoke training for your institution • Meeting room: a venue in Brussels

4. In addition… • UKRO training and development programme: complementing annual visits • UKRO Annual Conference: a key event for EU policy and networking • UK National Contact Point:for the Marie Curie Actions and the European Research Council • European RTD Insight: Free monthly publication funded by the British Council

6. What is Horizon 2020? • The EU funding programme for research and innovation from 2014 to 2020 • Budget of €70.2 billion • From research to innovation – from basic research to bringing ideas to the market • Focus on societal challenges EU society is facing (e.g. health, clean energy, food security, integrated transport) • Promise of simplified access for all

7. UK performance in FP7 • As at July 2013: • UK-based organisations have been awarded €5.2 billion of FP7 funding, (the second highest share by country, after Germany), equivalent to 15% of the programme’s overall budget • Academic organisations were awarded 62% of this share (thus 10.9% of the entire FP7 budget went to UK academia), and around 17% to SMEs • UK organisations were involved in around 8100 funded projects (the highest number by country) • The highest number of European Research Council grants went to the UK, with around 800 grants based at over 75 different host institutions

8. From FP7 to Horizon 2020 FP7 Horizon 2020 • Integrates FP, EIT, CIP • Societal Challenges • Strong industry focus overall • Covering the entire cycle from basic idea to market • Single reimbursement rate for all • Framework Programme • Research themes • SME participation important • Growing importance of innovation • Range of funding rates, complex rules

9. Horizon 2020 structure Widening Participation; Science with and for Society European Institute of Innovation and Technology (EIT) Joint Research Centre (JRC) EURATOM

10. Horizon 2020: how is it different? • Challenge-based, aims to allow freedom to come up with innovative solutions • Fewer topics but broader, less prescriptive topics • Cross-cutting issues embedded (e.g. social sciences, gender, INCO) • Simplified presentation (“common look and feel”) • Aim to be relevant to wider range of participants and to provide easy access to newcomers

11. Who will be eligible for funding? • 28 EU Member States (Croatia joined in 2013) • Associate Countries (similar list to FP7 expected) • Still under negotiation • Some might not sign agreement in time for Horizon 2020 start but can still apply as long as the agreement is signed in time for grant signature. • Third countries (funding will depend on GDP) • BRIC countries no longer eligible for automatic funding

12. Horizon 2020 Pillar 1 – Excellent Science

13. ERC in Horizon 2020 – What can be funded? • The ERC seeks to fund the best ‘frontier research’ proposals submitted by excellent researchers in the area of their choice. • Will fund projects led by a Principal Investigator, if necessary supported by a research team (no requirement for collaboration or forming consortia across different EU countries). • 25 panels in 3 domains which proposals can be submitted to: • Physical Sciences and Engineering (PE) • Life Sciences (LS) • Social Sciences and Humanities (SH)

15. ERC in Horizon 2020– Five Schemes

16. ERC in Horizon 2020 – should I apply? Starting Grants Who is a competitive candidate? • Must be able to show potential for excellence and evidence of maturity: • expectation for at least one important publication without the participation of the PhD supervisor • promising track record of early achievements appropriate to field and career stage, including: • significant publications (as main author) in major international peer-reviewed journals • and/or monographs • invited presentations, granted patents, awards, prizes etc • good leadership potential and must convince the ERC panel that the PI will be able to lead an ambitious ‘frontier research’ project

17. ERC in Horizon 2020 – What type of research projects can be funded? Proposals evaluated solely on the basis of excellence (excellence of the PI and of the research project), and should address: • Extended Synopsis (5 pages) • Scientific Proposal (15 pages) • To what extent does the proposed research address important challenges? • To what extent are the objectives ambitious and beyond the state of the art? • How much is the proposed research high risk/high gain? • To what extent is the outlined scientific approach feasible? • To what extent is the proposed research methodology appropriate to achieve the goals of the project? • To what extent does the proposal involve developing novel methodology? • To what extent are the proposed timescales and resources necessary and properly justified? * please note that this is the wording from the 2013 ERC calls

18. ERC Calls in 2014 (very likely call dates)

19. Horizon 2020 Marie Skłodowska-Curie Actions

20. MSCAin Horizon 2020 • Operates in a ‘bottom-up’ basis, open to all research and innovation areas • Mobility is a key requirement • Key areas supported: • Fostering new skills by means of excellent initial training of researchers • Nurturing excellence by means of cross-border and cross-sector mobility • Stimulating innovation by means of cross-fertilisation of knowledge • Co-funding of activities

21. MSCA – 4 Schemes

22. Innovative Training Networks • Major differences compared to FP7 • Participants defined as ‘academic’ and ‘non-academic’ • Early stage researchers (ESRs) only • The Innovative Doctoral Programme strand moved to the COFUND scheme • The ITN scheme consists of 3 strands

23. Individual Fellowships • Mobility rule for the career re-start panel “researchers shall not have resided or carried out their main activity in the country of their host organisation for more than 3 years in the 5 years immediately prior to the relevant deadline”

24. MSCA Calls for 2014-15

25. Overview of FET Activities • Expanded from ICT and Energy to be used as cross-cutting funding scheme • Supports frontier research: alternative ideas, concepts or paradigms of risky or non-conventional nature Open, light and agile Roadmap based research High-Performance Computing (HPC) Strategy Developing the next generation towards exascale 3 call topics

26. Horizon 2020 Pillar 2 – Industrial Leadership

27. Pillar 2 – Industrial Leadership

28. Leadership in enabling and industrial technologies (LEIT) • Strong focus on industrial involvement and applied research • Developing industrial capacity in focus areas: • Key Enabling Technologies (KETs) • Micro- and nano-electronics • Photonics • Nanotechnologies • Advanced Materials • Biotechnology • Advanced Manufacturing and Processing

29. What are Joint Technology Initiatives (JTIs)? • JTIs support large-scale multinational research activities in areas of major interest to European industrial competitiveness and issues of high societal relevance • Long-term public-private partnerships - combining private sector investment with European public fundingand sometimes also national funding • Set up as separate legal entity (Joint Undertaking)

30. Joint Technology Initiatives in Horizon 2020 • Led by industry, but open to new partners from universities and research institutes • Calls launched and managed by the Joint Undertaking • Same reimbursement rate as in rest of Horizon 2020 will apply (some derogations)

31. Innovative Medicines Initiative 2 (IMI2) “Improving the health and well-being of European citizens by providing new and more effective diagnostics and medicines, while helping safeguard the international competitiveness of the European biopharmaceutical industry.” • Increase the success rate in clinical trials of priority medicines Reduce the time to reach clinical proof of concept in medicine development • Develop new therapies for diseases for which there is a high unmet need • Develop diagnostic and treatment biomarkers for diseases clearly linked to clinical relevance and approved by regulators • Reduce the failure rate of vaccine candidates in phase III clinical trials • Improve the current drug development process

32. Joint Technology Initiatives in Horizon 2020

33. ICT in LEIT - Challenges New generation of components and systems Advanced Computing Future Internet Content technologies and information management Robotics Micro- and nano-electronic technologies/ Photonics Cross-cutting and horizontal activities and International Co-operation Future Internet Public Private Partnership • See draft 2014 Work Programme at: • http://www.ukro.ac.uk/subscriber/Pages/131107_draft_ict_wp_public.aspx

34. ICT in Societal Challenges • Health:e-health, self management of health, improved diagnostics, improved surveillance, health data collection, active ageing, assisted living; • “Advancing active and healthy ageing with ICT: Service robotics within assisted living environments” • “Advancing active and healthy ageing with ICT: early risk detection and intervention” • “Advanced ICT systems and services for integrated care” • “self-management of health and disease: decisional support systems and patient empowerment supported by ICT • Food: • Ocean observation technologies “Acoustic and imaging technologies” • “Forecasting and anticipating effects of climate change on fisheries and aquaculture” • “Improved data and management models for sustainable forestry”

35. New SME Instrument • Replaces Research for Benefit of SMEs scheme • Dedicated SME instrument • Target highly innovative SMEs looking to develop and grow in international environment • Funding awarded to single company, but projects can be collaborative • Allows for outsourcing of research • Three-stage support through innovation cycle • One project can access all three in order • One application per year

36. SME Instrument: How it Works • Stage 1: Feasibility • 6 month project • ~ €50k lump sum funding • to assess technological / commercial potential of project • Stage 2: Innovation Activity • 12 – 24 month duration • €1m - €3m funding • Emphasis on demonstration and market replication • Stage 3: Commercialisation phase • No direct funding • Simplified access to debt and equity financial instruments • Assistance with IPR protection

37. Horizon 2020 Pillar 3 – Societal Challenges

38. Societal Challenges rationale • Concerns of citizens and society + EU policy objectives • Breakthrough solutions come from multi-disciplinary collaborations, including social sciences and humanities • Addressing challenges requires full research & innovation cycle, from research to market • Focus on policy priorities without predetermining technologies or types of solutions to be developed

39. Focus Areas

40. Societal Challenges – Focus Areas 2014-15 Sept June Dec

41. H2020 Context – Health Challenge ~ 25% • “Effective health promotion, supported by a robust evidence base, prevents disease, contributes to wellbeing and contains costs” • Societal challenge to adjust to further demands on health and care sectors – support integrated care

42. Specific Priorities • Understanding health, wellbeing and disease • Understanding the determinants of health, improving health promotion and disease prevention • Improved understanding of health and disease • Improving surveillance and preparedness • Preventing Disease • Developing effective prevention and screening programmes + assessment of disease susceptibility • Improving diagnostics and prognosis • Better preventive and therapeutic vaccines

43. Specific Priorities • Treating and managing disease • Treating disease, including developing regenerative medicine • Transferring knowledge to clinical practice and scalable innovation actions • Active ageing and self-management of health • Active ageing, independent and assisted living • Individual awareness and empowerment for self-management of health

44. Specific Priorities • Methods and data • Improving health information and better use of health data • Improving scientific tools and methods to support policy making and regulatory needs • Using in-silico medicine for improving disease management and prediction • Health care provision and integrated care • Promoting integrated care • Optimising efficiency and effectiveness of healthcare provision and reducing inequalities by evidence-based decision making

45. Challenge 1: Health, demographic changes and well being 2014-2015 Calls divided into 8 specific activity areas: • Understanding health, aging and diseases • Effective health promotion, diseases prevention, preparedness and screening • Improving diagnosis • Innovative treatments and technologies • Advancing active and healthy aging • Integrated, sustainable, citizen-centred care • Improving health information, data exploitation and providing an evidence base for health policies and regulation • Co-ordination activities e.g. AHA EIP; More years, Better Lives; Global Alliance for Chronic Diseases

46. Health Topics Across H2020

47. Horizon 2020 Health - Context EIP Active and Healthy Ageing Health, Demographic Change and Wellbeing Health for Growth More Years, Better Lives Neurodegenerative Disease Antimicrobial Resistance Structural Funds Ambient Assisted Living Research Innovation Deployment

48. Joint Programming Initiatives • Initiatives led by EU Member States which combine aspects of national research programmes • Address major societal challenges • Aim to reduce fragmentation and avoid duplication • 10 JPIs have been established to date • JPIs establish Strategic Research Agendas and are likely to have an influence on Horizon 2020 work programme development

49. Joint Programming Initiative on More Years, Better Lives (JPI MYBL) • Seeks to improve coordination and collaboration between European and national research programmes related to demographic change • = National research councils pooling funding and launching joint calls. First joint activity launched in early 2013, on mapping the range of data sources on ageing in Europe. • Definition of demographic change covers: health to social welfare, education & learning, work & productivity to housing, urban & rural development and mobility. • 13 European countries are currently participating, including the UK through the ESRC. See: http://www.jp-demographic.eu/ for more details.

50. European Innovation Partnerships: Example of Active and Healthy Ageing • Initiatives which bring together wide range of partners to address a particular societal challenge. Not a funding instrument. • Overarching target of the EIP AHA is to increase, by 2020, the average healthy lifespan in the EU by 2 years. • Strategic Implementation Plan identifies 14 priority areas. Action Groups and online ‘Marketplace’ are up and running. • EIP aims and objectives will be reflected in Horizon 2020 work programmes. • See EIP AHA website: http://ec.europa.eu/research/innovation-union/index_en.cfm?section=active-healthy-ageing