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Infertility Management and Referral. Laura Neale. History and Examination. Unprotected sex 1 year (unless known problems) Primary or secondary Predisposing factors Menstrual cycle STIs Previous ectopics Galactorrhoea/hirsutism/acne Systemic diseases
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Infertility Management and Referral Laura Neale
History and Examination • Unprotected sex 1 year (unless known problems) • Primary or secondary • Predisposing factors • Menstrual cycle • STIs • Previous ectopics • Galactorrhoea/hirsutism/acne • Systemic diseases • Drug history (NSAIDs, chemotherapy, neuroleptics) • Lifestyle factors • BMI • Features of PCOS
Investigations (1) • Think in terms of cause Anovulatory Male factor Unexplained Tubal Other
Investigations (2) • Day 2-5 FSH and LH • Day 21 progesterone • Semen analysis • Rubella screen • Chlamydia screen
Investigations (3) • If anovulatory • TFTs • Prolactin • Oestradiol • Testosterone • SHBG • Assess tubal status (unless semen analysis abnormal)
Counselling • Optimise weight • Usual lifestyle advise • Folic acid • Investigative course • Costs (emotional and financial) • Chances failure (i.e. only 15% success rate per IVF cycle if age > 36)