Regulation of Gene Expression in Prokaryotes

Chapter 16 Lecture Concepts of Genetics Tenth Edition Regulation ofGene Expressionin Prokaryotes Chapter 3 Lecture Chapter 3 Lecture

16.1 Prokaryotes Regulate Gene Expressions in Response to Environmental Conditions

16.2 Lactose Metabolism in E. coli Is Regulated by an Inducible System

Figure 16.1

16.2 Lactose Metabolism in E. coli Is Regulated by an Inducible System • Structural Genes

Figure 16.2

Figure 16.3

Figure 16.4

16.2 Lactose Metabolism in E. coli Is Regulated by an Inducible System • The Discovery of Regulatory Mutations

16.2 Lactose Metabolism in E. coli Is Regulated by an Inducible System • The Operon Model: Negative Control

Figure 16.5

Figure 16.5a

Figure 16.5b

Figure 16.5c

Figure 16.6a

Figure 16.6b

17.2 Lactose Metabolism in E. coli Is Regulated by an Inducible System • Genetic Proof of the Operon Model

constitutive trans element cis element Table 16.1

Figure 16.7

16.3 The Catabolite-Activating Protein (CAP) Exerts Positive Control over the lac Operon

Figure 16.8

Figure 16.8a

Figure 16.8b

Figure 16.9

16.4 Crystal Structure Analysis of Repressor Complexes Has Confirmed the Operon Model

Figure 16.10

Figure 16.11c

16.5 The Tryptophan (trp) Operon in E. coli Is a Repressible Gene System

Figure 16.12

Figure 16.12a

Figure 16.12b

Figure 16.12c

16.6 Attenuation Is a Critical Process during the Regulation of the trp Operon in E. coli

Figure 16.13

Figure 16.13ab

Figure 16.13c

Figure 16.13d

TRAP and AT Proteins Govern Attenuation in B. subtilis TRAP = trp RNA-binding attenuation protein AT = anti-TRAP

Figure 16.14

Figure 16.14a

Figure 16.14b

16.7 Riboswitches Utilize Metabolite-sensing • RNAs to Regulate Gene Expression

16.8 The ara Operon Is Controlled by a Regulator Protein That Exerts Both Positive and Negative Control

Figure 16.16

Figure 16.16a

Figure 16.16b

Figure 16.16c

Regulation of Gene Expression in Prokaryotes