1 / 3

Glucose (25 mM) - + - + - + - + -

Glucose (25 mM) - + - + - + - + - Mannitol (25 mM) - - + - + - + - + GBE (100  g/ml) - - - + + - - - -

teal
Download Presentation

Glucose (25 mM) - + - + - + - + -

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript

  1. Glucose (25 mM) - + - + - + - + - Mannitol (25 mM) - - + - + - + - + GBE (100 g/ml) - - - + + - - - - NAC (1 mM) - - - - - + + - - Staurosporine (100 nM) - - - - - - - + + Glucose (25 mM) - + - + - + - + - Mannitol (25 mM) - - + - + - + - + GBE (100 g/ml) - - - + + - - - - NAC (1 mM) - - - - - + + - - Staurosporine (10 nM) - - - - - - - + + NF- B AP-1 Supplement Figure 1, Pretreatment with GBE has no significant effects on chronic high-glucose- induced AP-1 and NF-B activation in HEACs. Staurosporine, a PKC inhibitor.

  2. Supplement Figure 2, Pretreatment with GBE does-dependently suppressed high glucose-induced ICAM-1 accumulation in HAECs.

  3. Supplement Figure 3, Endothelial ICAM-1 expression was increased by high-glucose (25mM) stimulation for 4 days, which was losing after the replacement of normal glucose medium (5mM) for 1-4 days.

More Related