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GLOMERULAR DISEASE.

GLOMERULAR DISEASE. BY DR GHULAM HUSSAIN. MBBS, Diploma in Cardiology, MD (Medicine) Assistant Professor of Medicine Medical Unit-4 LUMHS, Jamshoro / Hyderabad . A. Hereditary Nephritis. Inheritance and Incidence :

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GLOMERULAR DISEASE.

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  1. GLOMERULAR DISEASE. BY DR GHULAM HUSSAIN. MBBS, Diploma in Cardiology, MD (Medicine) Assistant Professor of Medicine Medical Unit-4 LUMHS, Jamshoro / Hyderabad

  2. A. Hereditary Nephritis Inheritance and Incidence : Hereditary nephritis is inherited as An X-linked or autosomal dominant trait with variable penetrance. 2. Clinical Features: Hematuria High frequency sensorineural hearing loss 3. Therapy and Prognosis:

  3. B. Minimal Change Disease (Lipoid nephrosis, nil lesion nephrotic syndrome Incidence Pathology Clinical Features Nephrotic syndrome is the typical presentation by patients of all ages. Hypertension occurs in 10% of children and 35% in adults. Hematuria is uncommon Azotemia develops in 23% of children and in 34% of adults.

  4. 4. Therapy Glucocorticoids Cytotoxic Agents Cyclosporine Cyclosporine 5. Prognosis

  5. C. Membranous Glomerulonephritis Etiology Primary (Idiopathic) Membranous Glomerulonephritis Secondary Membranous Glomerulonephritis (1) Infection (2) Rheumatic disease (3) Neoplasm (4) drug Therapy

  6. 2. Pathology 3. Clinical Features 4. Clinical Course 5. Therapy

  7. 6. Complications A hypercoagulable Intra Vascular Volume depletion Hypertension, Obstruction, Infection

  8. D. Mesangial Proliferative Glomerulonephritis Etiology The cause is unknown Pathology Clinical Features Clinical Course Therapy

  9. E. MembranoproliferativeGlomerulonephritis Incidence and Etiology Pathology Clinical Features Clinical Course Therapy

  10. F. Focal Glomerulosclerosis Incidence and Etiology Pathology Clinical Features Therapy

  11. G. Goodpasture’s Syndrome Defination Clinical Features and diagnosis Clinical Course Therapy

  12. H. Idiopathic CrescenticGlomerulonephritis Incidence and Etiology Clinical Features Diagnosis Clinical Course and prognosis Therapy

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