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Anaphylactic Shock & Allergy. B9902017 李佳倫 B9902024 林君翰. Allergy. A hypersensitivity disorder of the immune system The first symptom appears on the skin: swelling, being red, and usually accompanied with hey fever. Patients may feel anxious, stomachache and diarrhea. Causes. Food
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Anaphylactic Shock & Allergy B9902017李佳倫 B9902024林君翰
Allergy • A hypersensitivity disorder of the immune system • The first symptom appears on the skin: swelling, being red, and usually accompanied with hey fever. • Patients may feel anxious, • stomachache and diarrhea.
Causes • Food Ex. peanut, tree nuts, shellfish, fish, milk, and Ex. egg • Medication Ex. antibiotics, aspirin, ibuprofen, and other Ex. analgesics • Venom Ex. stinging or biting insects
Different Kinds of Allergy • TypeⅠ : Immediate hypersensitivity • TypeⅡ : Antibody mediated diseases • TypeⅢ : Immune complex mediated diseases • TypeⅣ : T cell mediated diseases
The Mechanism in cell IgEattach to the mast cell → mast cells release a large number of chemical substances → the allergic reaction within the body.
Anaphylactic Shock • Also called “Anaphylaxis” • An acute multi-system severe allergic reaction. • Systemic vasodilation →low blood pressure (80/50mmHg) • Severe bronchoconstriction → individual is unable to breathe
Anaphylaxis can be divided into two : • "true anaphylaxis" ---caused by mast cells or basophils mediated by IgE • "pseudo-anaphylaxis" ---occurs without IgE mediation. • The symptoms, treatment, and risk of death are the same
Management • Administration of epinephrine • Intravenous fluids • supplemental oxygen • Preparedness Ex. Prepare epinephrine auto-injectors Wear a medical alert bracelet
Special Thanks • http://www.freegroup.org/2008/10/free-powerpoint-templates-templateswise/ • http://www.live-in-green.com/health_info/allergy/types/emergencies_c.html • http://big5.wiki8.com/guominxingxiuke_20204/ • http://en.wikipedia.org/wiki/Type_II_hypersensitivity -And- • Basic Immunology – Abul K. Abbas & Andrew H. Lichtman