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Explore the study of heredity, Gregor Mendel's contributions, and key concepts in genetics such as true breeding, laws of segregation and independent assortment, monohybrid and dihybrid crosses, sex-linked inheritance, Punnett squares and pedigrees, modes of dominance, and polygenic inheritance.
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Mendel & GeneticsReview Powerpoint • Gregor Mendel, the father of genetics.
Genetics is the study of… • heredity
Define Heredity. • The passing on of traits from one generation to the next.
Where is genetic information stored? • DNA Specifically, in each individual’s DNA on chromosomes that contain many genes.
What did Mendel study to understand inheritance? • Common garden pea plants • Why did he choose pea plants? • 1--Fast growing with many offspring = quick results • 2—Sexually Reproduce and male as well as female reproductive organs in each plant • 3—Traits come in a dichotomy—only two forms. • Like tall and short or green and yellow
What did Mendel call true breeding? • Plants that come from a long line of plants that show the same trait • When he crossed two true-breeding plants with opposite traits, he called this what? • The “P” cross for Parental generation
What two individuals did Mendel cross in the P generation? • True-breeding Tall and Short pea plants • Genotypes? • Tall = TT • Short = tt
What resulted in the F1 generation? • Pea plants that were… • Phenotypes? • All TALL • Genotype? • All “Tt”
What was Mendel’s next step? • He crossed two F1 plants. • What results did he get? • The F2 generation • What interesting ratio did he find? • They were 3:1 (dominant to recessive)
What is the Law of Segregation? • 1--Individuals must have two copies of genetic information for every trait– one from each parent • 2—each copy is passed randomly • 3—One of these copies (alleles) can mask the expression of the other, ie. Dominant alleles can mask recessive alleles when both are present
What is the Law of Independent Assortment? • Alleles of different genes separate independently of one another during gamete formation • What does that mean? • The allele a parent gives for one trait does not affect what he/she gives for another trait so you can have many different combinations of traits given to the egg or sperm
What are alleles? • Different forms of the same gene for a trait • When an individual has two of the same allele, the genotype is called… • Homozygous • When there are two different alleles, it is… • Heterozygous
What is the difference between genotype and phenotype? • Genotype is • the type of genes or alleles • Phenotype is • What is looks like--The physical appearance of the organism
Monohybrid vs. Dihybrid • Mono hybrid: a cross when there is just one trait involved, ex. • Height: Tt X tt • Di hybrid: Two traits are involved, ex. • The horse’s coat and gait are crossed • FFGg X Ffgg
Sex-linked Inheritance • Autosomes are chromosomes not on the.. X or y chromosomes • Sex-linked characteristics are always on… • The X-chromosome • Give an example of a sex-linked condition • Hemophilia • Why does it occur more in males? • Males only inherit 1 X-chromosome so there is a better chance they would express (whether its dominant or recessive) the condition.
Contrast a Punnett Square and a Pedigree • A Punnett Square is… • a grid that predicts the types of possible offspring from a cross • A Pedigree is.. • A diagram that shows a family tree and how traits pass from generation to generation
Modes of Dominance: • 1--Complete dominance… • One allele is completely dominant over the recessive and the recessive is masked in a heterozygous individual • 2--Incomplete dominance.. • The dominant does not completely mask the recessive and the heterozygous phenotype is a blend of the two- an intermediate variation. • There are three possible phenotypes.
More modes of inheritance • 3-- Co dominance.. • More than one genotype is dominant and when two of these are together, they form another phenotype • 4–Multiple alleles.. • These traits have 3 or more alleles • Example of both codominance and multiple alleles.. • blood types. How many blood types are possible? • Four-- They are.. • A, B, AB, and O
Modes of Inheritance cont. • 5-- Polygenic Inheritance: traits that are.. • controlled by multiple genes pairs. • This makes many variations of color and trait possible • What are characteristics controlled by multiple pairs of alleles? • Human hair and eye color