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Sildenafil Citrate The ace in treating erectile dysfunction in men
A glimpse on the molecule • Sildenafil citrate is a drug of choice for men who are suffering from Erectile Dysfunction (ED). • It is widely available all around the world • It is the active pharmaceutical ingredient of Viagra and all its generic versions • It is a safe and effective drug which is approved by the FDA for treatment of ED.
A glimpse on the molecule • It is classified under class of drugs referred to as PDE5 inhibitors. • It is a very popular choice among men suffering from ED due to its extremely low rates. • The effects of the drug can be seen 45 minutes-1 hour after ingesting the drug. • The duration of action of sildenafil citrate is 4-5 hours.
Mechanism of Action • The active component of Generic Viagra dissolves quickly in the blood to exhibit its action at the site of action. • It inhibits the action of the enzyme PDE5 in the body. • This leads to a sudden increase in the levels of Nitric Oxide in the body. • When this happens, the production of the enzyme cGMP also increases rapidly. • This causes the arteries in the penile region to dilate and allow increased flow of blood to the penis. • Thus, men get hard erections which also can last for extended duration in order for them to enjoy sexual intercourse.
Doseand Usage • Ideally the commonly suggested dose of sildenafil is 100mg tablet, once a day. • This tablet should be taken with a glass of water. • Never chew, crush or break the tablet before consumption. • This tablet is best to be taken 1 hour before indulging in sexual action. • Maintaining a 24-Hour gap between two doses is extremely important. • This medicine should be taken only when one is stimulated enough to indulge in sexual intercourse, as the drug does not help in sexual arousal.
Side effects • Nausea • Headache • Dizziness • Vomiting • Blurry eyes • Facial flushing • Nasal congestion • Muscle cramps • Breathlessness • Chest pain • Prolonged erection of over 4 hours • Hives • Swelling of the face, tongue and limbs.
Precautions • It is always best to start this medicine after taking a doctor’s approval and guidance. • It is considered best to avoid the following while taking generic Viagra: • Alcohol • Tobacco • Grapefruit products • Nitrate drugs • Alpha-blockers • Other PDE5 inhibitors
Precautions • It is best to avoid outdoor activities or indulging in activities which need high mental alertness. • Never overdose on this medicine. • Always consume this medication only if you are suffering from erectile dysfunction. • Strictly to be avoided in children, teenagers and women.
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