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Meiosis and Sexual Lifecycles. Chapter 13. Objectives. Understand the meaning of “SEX” Understand the process of meiosis Understand the need to undergo meiosis as sexual organisms. Need For Sex. Sex: results in the recombination of genetic information
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Meiosis and Sexual Lifecycles Chapter 13
Objectives • Understand the meaning of “SEX” • Understand the process of meiosis • Understand the need to undergo meiosis as sexual organisms
Need For Sex • Sex: results in the recombination of genetic information • Organisms with sexual lifecycles have a greater range of genetic variation that may result in a greater ability to adapt to an environment • Meiosis is key to enhancing this variation
Sex Terms • Diploid: having 2 of each chromosome type • Haploid: having a single representative of each chromosome type • Homologous chromosomes (homologues): chromosomes from different parents that are of the same type (contain similar information) • Sister Chromatids: 2 “identical” strands of DNA connected by a centromere that contains a kinetochore. Makes up each member of a homologous pair
Mitosis produces 2 daughter cells daughters are clones of the parent daughter cells are diploid growth, replacement, repair Meiosis produces up to 4 daughter cells daughters are distinct from parents daughter cells are haploid generation of gametes (sex cells): egg & sperm Comparison
Meiosis (the process) • Meiosis: nuclear division with a reduction in chromosome number by half • Two parts to the process • Meiosis I: separation of homologous pairs • Meiosis II: separation of sister chromatids (just as in mitosis)
Meiosis I • Prophase I: same as mitosis • Metaphase I: both members of a homologous pair arrange themselves as a tetrad (synapsis) along the metaphase plate; crossover (chiasma) may occur • Anaphase I: Kinetochore remains intact and homologous pairs are separated as spindle fibers shorten
Meiosis II • Telophase I: same as mitosis (includes cytokinesis) • Meiosis II is the same process as mitosis except starting from Telophase I instead of Interphase • no doubling of DNA has occurred • Result is up to four daughter cells
Genetic Variation • Variation in the DNA of a zygote can be induced by three different methods occurring the during sexual cycle • Random fertilization: 8+ million possible combinations of sperm and egg = 70,368,744,000,000 possible combinations • Independent Assortment • Crossing over
Independent Assortment • There are about 8 million possible combinations of chromosomes based on random assortment of the different types in the human genome (8,388,744). • This occurs during Anaphase I of meiosis as homologous pairs are separated • Genes that do not reside on the same chromosome may sort independent of one another
Crossing Over • During tetrad formation (Prophase I) chromosomes may cross (chiasma). • Sometimes genetic information may be exchanged between homologues further shuffling the genetic information of the eventual gamete (4,951,760,200,000,000,000,000,000,000 different zygotes with a single crossover)