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FARMACOLOGÍA

FARMACOLOGÍA. INTEGRANTES: DIAZ BENEL, NANCY. POMA CABRERA, MILAGROS. ROJAS GARRO, SANDRA TALIA. Corticoides. INTRODUCCION. TIPOS Y LUGAR DE PRODUCCIÓN:. EFECTOS METABOLICOS. REGULACIÓN. Glucocorticoides S istema hipotalámico-hipofisario-adrenal.

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FARMACOLOGÍA

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  1. FARMACOLOGÍA INTEGRANTES: DIAZ BENEL, NANCY. POMA CABRERA, MILAGROS. ROJAS GARRO, SANDRA TALIA.

  2. Corticoides

  3. INTRODUCCION

  4. TIPOS Y LUGAR DE PRODUCCIÓN:

  5. EFECTOS METABOLICOS

  6. REGULACIÓN • Glucocorticoides • Sistema hipotalámico-hipofisario-adrenal. • CRH-hormona liberadora de corticotropina • ACTH:Adrenocorticotropina. • Cortisol-transcortina. • Retroalimentación negativa • Mineralcorticoides • El sistema renina-angiotensina

  7. RESPUESTA ANTIINFLAMATORIA

  8. Resumen

  9. Resumen

  10. Inmunosupresores

  11. Corticoesteroides:

  12. Mecanismo de acción: • Dominios: • *C-terminal de union al ligando. • *central de union al AND. • N-terminal- cap. De activar la transcripcion.

  13. CORTICOSTEROIDES SINTETICOS • Mas potente • Mayor semivida que los naturales • Especifico de un solo tipo de receptor

  14. CORTICOIDES MAS UTILIZADOS

  15. Tratamiento en Enfermedades Reumaticas

  16. Suspensión del tratamiento

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