1 / 9

Drug Delivery Chip

Drug Delivery Chip. Jonathan Ims BME 281 Sec. 1. History of the Drug Delivery. 1964, Folkman demonstrated a silicon rubber pill for low molecular weight drugs. 1970s, Langer expanded on Folkman Polymers that could carry macromolecules

trina
Download Presentation

Drug Delivery Chip

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript

  1. Drug Delivery Chip Jonathan Ims BME 281 Sec. 1

  2. History of the Drug Delivery • 1964, Folkman demonstrated a silicon rubber pill for low molecular weight drugs. • 1970s, Langer expanded on Folkman • Polymers that could carry macromolecules • Mid 1990’s the idea of a drug releasing microchip by J. Santini Jr. • J. Santini Jr. went to MIT

  3. Types of Pumps • Mechanical Micro Pumps • Need a physical actuator • Non-mechanical Micro Pumps • Converts some form of energy into kinetic momentum • Key components • High Flow Rate • Low Voltage (between 5 -12V) • Reliability of the System • Bio-compatibility • Frequency

  4. How the Reservoirs Are Made

  5. Drug Delivery Chip Using Electrolysis

  6. Characteristics of the Drug Deliver Chip • The width and length of each chip varies but the depth of the chip remains between (0.5mm to 1mm) • 8 reservoirs can be found in an area of 1.77mm by 1.44mm • The reservoirs can hold a total of 200nL

  7. Who are the Drug Delivery Chips Intended For? • Patients with Chronic Disease • Diabetes • Epilepsy • Osteoporosis • etc. • It is not meant to replace prescription pills for common illnesses such as the flu.

  8. Limitations • Surgery • Unwanted Side Effects • Heat • Pressure • pH • Bio-compatibilty • Reservoir size

  9. Future Plans • Increase the efficiency of drug delivery • Self-drug releasing chips • Different types of drug release • Better bio-materials

More Related