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BALF. BLM 2 mg/kg i.t. or Saline i.t. BALF or Sacrifice. Day 0. Day 7. Day 14. Experiment 1 (Effects of olmesartan medoxomil). BLM + Vehicle. Vehicle (p.o.). BLM + OL (0.1). olmesartan 0.1 mg/kg/day (p.o.). BLM + OL (1). olmesartan 1 mg/kg/day (p.o.). Saline + OL (1).

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  1. BALF BLM 2 mg/kg i.t. or Saline i.t. BALF or Sacrifice Day 0 Day 7 Day 14 Experiment 1 (Effects of olmesartan medoxomil) BLM + Vehicle Vehicle (p.o.) BLM + OL (0.1) olmesartan 0.1 mg/kg/day (p.o.) BLM + OL (1) olmesartan 1 mg/kg/day (p.o.) Saline + OL (1) olmesartan 1 mg/kg/day (p.o.) Saline + Vehicle Vehicle (p.o.) Experiment 2 (Effects of PD-123319) BLM + Saline Saline (s.c.) BLM + PD (0.5) PD-123319 0.5 mg/kg/day (s.c.) BLM + PD (5) PD-123319 5 mg/kg/day (s.c.) Saline + PD (5) PD-123319 5 mg/kg/day (s.c.) Saline + Saline Saline (s.c.)

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