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Strategic Framework. Side Effects & Advanced Biotechnology. Novel Diagnostic Target Proteins & Therapeutic Compounds. Compounds, Peptide modulators, Protein Drug Design System. Drug Efficacy Evaluation System. Technology Integration.
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Strategic Framework Side Effects & Advanced Biotechnology Novel Diagnostic Target Proteins & Therapeutic Compounds Compounds, Peptide modulators, Protein Drug Design System Drug Efficacy Evaluation System Technology Integration Protein-Drug Binding Site Mapping Protein-Protein Interaction Mapping Statistical & Geometric Modeling High Performance Computing Data Base Data Mining Technology Base Information Science Mathematics & Statistics Life Science Knowledge Base
Vision • Many drugs have strong efficacy for diseases which were not originally targeted. • Side effects of drugs often arise from binding of drugs to unintended proteins targets. • We systematically examine potential efficacy of every prescription drug to every protein structure, with a planned comprehensive mapping of protein surfaces and drugs contained in the global atlas of protein targets for all existing prescription drugs. • We envision a disruptive technology for drug discovery by the integration of engineering principles, information and various forms of biological data.