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Causes of Disease. 4-H Veterinary Science Extension Veterinary Medicine Texas AgriLife Extension Service College of Veterinary Medicine and Biomedical Science Texas A&M System http://aevm.tamu.edu. Objectives . Distinguish between infectious and non-infectious causes of disease
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Causes of Disease 4-H Veterinary Science Extension Veterinary Medicine Texas AgriLife Extension Service College of Veterinary Medicine and Biomedical Science Texas A&M System http://aevm.tamu.edu
Objectives • Distinguish between infectious and non-infectious causes of disease • Discuss risk factors • Discuss primary cause factors • Discuss secondary cause factors
Infectious Diseases • Infectious disease • An illness due to a specific infectious agent or its toxic products that arises through transmission of that agent or its products from an infected person, animal or reservoir to a susceptible host, either directly or indirectly
Agents involved • Germs • Bacteria • Viruses • Fungi • Rickettsiae • Helminths • Protozoa • Arthropods
Damage caused • Feed off of body tissue • Reproduce in tissue • Release toxins • Pressure
Reproduction • Lag phase • Usually incubation period where organism is settling in to new surrounding • Growth phase • Exponential growth is rapid • Plateau phase • Growth = Death Plateau Phase Number of Organisms Growth Phase Lag Phase Time
Lag phase maybe long • Non-disease dormancy or latency • multiple when conditions are optimal or when organism is ready • May break if bacteria is in stressful environment • Bacteria and virus are precipitated by stress • Ex. Anthrax go into dormancy (spore form) when exposed to oxygen, once in anaerobic environment, bacteria multiply and cause fatal disease • Causes disease
Non-Infectious Disease • Disease cause • Dysfunction or disorder of reproductive disease • Example - hypo/hyper-thyroidism • Nutritional deficiencies or imbalances • Example - copper toxicity - damage liver • Chemical and plant poisoning • Example - acorns and green tomatoes • Physical injuries and stress
Causal pathway • Variables present B C C B D A A D H E E G F F Diseased Non-Diseased
Primary Cause • ALWAYS present when occurs and • Risk factors increase or decrease probability of disease in individual • Disease • Example - not washing hands after using restroom • Dysfunction • Example - cryptorchidism • Disorder • Example - type 1 diabetes - body does not produce enough insulin
Secondary Causes • Primary cause not as evident • Secondary is noticeable when individual is sick • Need tissue damage from primary cause • Invade and multiply Dividing Bacteria Video
Risk Factors • Causative factors • Increase chances of getting sick • Examples • Overcrowding • Pollution • Weather • Inbreeding
Protective factors • Decrease chances of getting sick • Examples • Vaccination • Husbandry • Crossbreeding • Good management practices