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Making Babies. Do Now: On Whiteboard. What is the difference between a genotype and a phenotype ? Which (genotype or phenotype) can you actually “see” with your eyes ? Which (genotype or phenotype) can only be seen on DNA/Chromosomes ?. Genotype. The combination of genes you receive.
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Do Now: On Whiteboard • What is the difference between a genotype and a phenotype? • Which (genotype or phenotype) can you actually “see” with your eyes? • Which (genotype or phenotype) can only be seen on DNA/Chromosomes?
Genotype • The combination of genes you receive
Phenotype • The features that result from your genes Red Red White
Cutting out your Chromosomes • Cut out each chromosome completely (both halves) • Ex. cut around both #1 • Fold each chromosome in half lengthwise • Place the chromosomes in your ziploc bag and label the bag with your name
X and Y Chromosomes • Males have X and Y chromosomes • Females have X and X chromosomes • Keep both your X and Y chromosomes just in case you need to simulate the other gender • Ex. two male students partner up, one uses X and X chromosomes
Making Your Sex Cells • To determine the facial appearance of your child, you and your partner will drop each of your 23 pair of chromosomes to the desktop to simulate random sex cell formation • This “dropping” will determine which one of the pair of chromosomes (which side will face up) will enter the successful sperm or egg cell • Each parent donates one AND ONLY ONE of each of their 23 pairs of chromosomes • Remember: gametes (sex cells) are made by meiosis • 4 daughter cells from one parent cell, each with only 50% DNA • ½ DNA from Mom + ½ DNA from Dad = 100% DNA for child
Fertilizing Sperm and Egg • After you drop your own chromosomes and line them up according to size (number), you will pair them up with your partner by pushing the chromosomes one at a time toward one another until they are side by side • This represents the establishment of pairs of chromosomes in the fertilized egg cell • ½ DNA from Mom + ½ DNA from Dad = 100% in Child • When you are done, you should have 23 pairs of chromosomes again • The mathematics of sex: one of each pair from mother + one of each pair from father = a pair of each kind for the baby
Data Table • Circle the genotype of each feature on your data table • Ex. Aa • Underline the phenotype of each feature on your data table • Ex. Brown eyes • Then, each student should produce a drawing of his or her child 15 years later when he or she is in high school.
Rubric • Cutting out chromosomes (4 pts) • Genotypes circled (4 pts) • Phenotypes underlined (4 pts) • Picture of your baby based on data (4pts) • Participation(4 pts) • Total = 20 pts towards laboratory grade