130 likes | 332 Views
Assembly and Deformation of the Bacterial Cell Wall. Rico Rojas Huang and Theriot Labs. Cell Morphogenesis – The cell wall defines cell shape. Spirochete Bacteria. Micrasterias. Phycomyces. Acetabularia. Pollen tube growth. Pulsatile pollen tube growth.
E N D
Assembly and Deformation of the Bacterial Cell Wall Rico Rojas Huang and Theriot Labs
Cell Morphogenesis – The cell wall defines cell shape Spirochete Bacteria Micrasterias Phycomyces Acetabularia
Actinhomologs orchestrate cell wall assembly in bacteria Jones 2001
Research Agenda What is the growth rate dependence on turgor pressure? What determines MreB localization?
What is the growth rate dependence on turgor pressure – varying the turgor pressure
Growth rate dependence on turgor pressure – computational framework Furchgott 2011
MreB Localization – MreB binds ATP and mutations around the nucleotide binding pocket affect MreB localization and cell shape in Caulobacter Dye 2011
Using MreB mutants as a perturbation to study localization C. crescentus E. coli WT D189G A325P