1 / 9

Drugs That Weaken the Bacterial Cell Wall I: Penicillins

Chapter 80. Drugs That Weaken the Bacterial Cell Wall I: Penicillins. Drugs That Weaken the Bacterial Cell Wall: Penicillins. Penicillins Weaken the cell wall, causing bacteria to take up excessive water and rupture Bactericidal Bacterial resistance

rservantes
Download Presentation

Drugs That Weaken the Bacterial Cell Wall I: Penicillins

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript

  1. Chapter 80 Drugs That Weakenthe Bacterial Cell Wall I:Penicillins

  2. Drugs That Weaken the Bacterial Cell Wall: Penicillins • Penicillins • Weaken the cell wall, causing bacteria to take up excessive water and rupture • Bactericidal • Bacterial resistance • Inability of penicillins to reach their target • Inactivation of penicillins by bacterial enzymes

  3. Classification of Penicillins Penicillins • Narrow spectrum • Pencillinase sensitive • Narrow spectrum • Pencillinase resistant • Broad spectrum • Extended spectrum

  4. Penicillin G (Benzylpenicillin) • Four forms • Sodium penicillin • Potassium penicillin • Procaine penicillin • Benzathine penicillin • Adverse effects • Allergy—penicillins are the most common cause of drug allergy

  5. Penicillin Allergy • Types • Immediate (2 to 30 minutes) • Accelerated (1 to 72 hours) • Late (days or weeks) • Anaphylaxis – Laryngeal edema – Bronchoconstriction – Severe hypotension

  6. Penicillin Allergy (cont.) • Treatment • Epinephrine • Respiratory support • Prevention—skin testing

  7. Penicillinase-Resistant Penicillins • Four agents • Nafcillin • Oxacillin • Cloxacillin • Dicloxacillin

  8. Broad Spectrum Penicillins (Aminopenicillins) • The aminopenicillins consist of three agents • Ampicillin • Amoxicillin • Bacampicillin • Adverse effects • Rash • Diarrhea

  9. Extended Spectrum Penicillins (Antipseudomonal Penicillins) • The extended spectrum penicillins consist of four agents • Ticarcillin • Carbenicillin indanyl • Mezlocillin • Piperacillin

More Related