Automated Gene Synthesis Machines

1. Automated Gene Synthesis Machines By Austin Burgess

2. What is a Gene • A gene is a unit of heredity that is transferred from a parent to its offspring and is held to determine some characteristics of the, “Proteins coded directly by genes”

3. What They Do • The genes, also known as oligonucleotides , took twenty years to make a automated gene synthesis machine. • They make oligonucleotides of high quality, to do a broad range of applications. Like the MerMade 192E pictured on the first slide.

4. What is Gene Therapy • Gene therapy is correcting genes responsible for disease development. • The most common form of gene therapy is placing a gene in a nonspecific location within the genome to replace a nonfunctioning gene.

5. The Risks of Gene Therapy • It can cause your immune system to attack the virus inserted causing organ failure and inflammation. • The virus may spread through more than one cell causing mutated cells and missing genes. • Finally it may introduce a tumor if they are inserted into the wrong spot in the genome, it could lead to a tumor.

6. How it Helps Gene Therapy • It synthesizes DNA into column format using standard or modified chemistries. • It takes about three hours to synthesize the DNA into its column format. • They can now use them to program what the gene’s function should be through a gene synthesizer.