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THE RESPIRATORY SYSTEM. Chapter 22. RESPIRATION. The exchange of gases between the atmosphere, lungs, blood, and tissues. Respiration. Pulmonary ventilation =“breathing” External respiration =occurs within the lungs Transport of respiratory gases =via the blood
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THE RESPIRATORY SYSTEM Chapter 22
RESPIRATION The exchange of gases between the atmosphere, lungs, blood, and tissues
Respiration • Pulmonary ventilation=“breathing” • External respiration=occurs within the lungs • Transport of respiratory gases=via the blood • Internal respiration=occurs within the tissues
REQUIREMENTS • Gas exchange surfaces must be thin. • Gas exchange surfaces must remain moist. • Gas exchange surfaces must be large in relation to the size of the organism.
FUNCTIONAL ANATOMY • Nose and nasal cavity • Pharynx • Larynx • Trachea • Bronchial tree • Lungs • Diaphragm
Tissue Changes Summarized • Pseudostratified ciliated columnar • Simple columnar • Cuboidal • Smooth muscle • Cartilage rings • Cilia • Simple squamous
Pressures • Atmospheric pressure • Alveolar pressure (intrapulmonary pressure) • Intrapleural pressure • Boyle’s Law • More volume=less pressure • Less volume=more pressure
Factors Influencing Pulmonary Ventilation • Airway Resistance • Surface Tension • Lung Compliance
Dead Space • Anatomical dead space • Alveolar dead space • Total dead space
Regulation of Respiration • Medullary respiratory center • Dorsal respiratory center (DRC) • Ventral respiratory center (VRC) • Pontine center formerly called the Pneumotaxic center • Hypothalamus
Basic Properties of Gases Dalton’s Law of Partial Pressures
Sinusitis Laryngitis Pleurisy Atelectasis Pneumothorax Dyspnea Pneumonia Infant respiratory distress syndrome (IRDS) Emphysema Chronic bronchitis Asthma Tuberculosis Cystic fibrosis Pulmonary embolism Sleep apnea Hypoxia Homeostatic Imbalances of the Respiratory System