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NCI Center for Modeling Cancer Development (CMCD) – Multiscale Modeling of the Breast Cancer TIC Niche. Stephen Wong with Zhou, X., Chauviere , A, Hatzikirou , H., Cristini , V., Lewis, M., Rosen, J.
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NCI Center for Modeling Cancer Development (CMCD) – Multiscale Modeling of the Breast Cancer TIC Niche Stephen Wong with Zhou, X., Chauviere, A, Hatzikirou, H., Cristini, V., Lewis, M., Rosen, J. The Methodist Hospital Research Institute, U Texas Health Science Center, Baylor College of Medicine, Texas Medical Center, Houston, TX
Modeling of the TIC Lineage Progenitor cells Terminal differentiated cells TICs ωTICPsy Niche TC … TIC PC1 PCk TC TC PC1 PCk ωTICPasy ωpc ωpc ωpc d2 d3 d1 d2 and - probabilities for symmetric and asymmetric divisions of TICs and - division rates for TIC and PC d1, d2 and d3- death rates of TICs, PCs and TCs