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VARIATIONS IN REFERENCE VALUES UTILIZED IN PULMONARY FUNCTION TESTS

Süleyman Savaş Hacıevliyagil, Levent Cem Mutlu, Gazi Gülbaş, Özkan Yetkin, Hakan Günen Inonu University Faculty of Medicine Department of Pulmonary Medicine Malatya, TURKEY. VARIATIONS IN REFERENCE VALUES UTILIZED IN PULMONARY FUNCTION TESTS. Introduction.

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VARIATIONS IN REFERENCE VALUES UTILIZED IN PULMONARY FUNCTION TESTS

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  1. Süleyman Savaş Hacıevliyagil, Levent Cem Mutlu, Gazi Gülbaş, Özkan Yetkin, Hakan GünenInonu University Faculty of Medicine Department of Pulmonary MedicineMalatya, TURKEY VARIATIONS IN REFERENCE VALUES UTILIZED IN PULMONARY FUNCTION TESTS

  2. Introduction Pulmonary function tests (PFT) are used to evaluate and stage the abnormalities in the functions of the respiratory system.

  3. Introduction • Results of PFT measurements are defined according to the comparisons made with the reference values obtained by using sex, height and age parameters in healthy individuals. • In our country, usually, Knudson’s reference values are used in PFT measurements.

  4. Aim The aim of this study is to investigate whether these reference values are suitable for our region or not.

  5. Material and Methods 311 non-smoker individuals living in Malatya, over 18, without any respiratory symptom or respiratory disease in the past were included in the study using stratified cluster sampling method.

  6. Material and Methods • All subjects performed forced vital capacity maneuver, and their PFTs were measured at least for three times. • FVC, FEV1, FEV1/FVC, FEF25-75and PEF parameters were used in our evaluations.

  7. Material and Methods For these parameters, new formulations deriving from regression curves were obtained using independent parameters age and height, separately for both sexes.

  8. Material and Methods The best PFT measurements were compared with the Knudson’s reference values using student-t test.

  9. Results • 311 participants • 189 males, 122 females • Age: 45.6±17.2 years

  10. Tartışma

  11. Conclusions • In conclusion, we have found some variations between the Knudson’s reference values and our PFT values obtained from healthy individuals in our region. • We think that the definition of accurate reference values in our country may enable the clinicians better evaluate the patients.

  12. Goal To achieve this goal, it is necessary to perform multicentric studies.

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