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Figure S1: Mathematical model of CD14 signaling pathway. Figure S2: Mathematical model of PI3K signaling pathway. Figure S3: Mathematical model of TNF signaling pathway. Figure S4: Mathematical model of EGF signaling pathway.
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(B) (A) Figure S6: Simulation graphs of (A) CD14 (B) TLR4
(A) (C) (B) Figure S7: Simulation graphs of (A) cytoplasmic NF-kappa B (B) EGF (C) TNF
(A) (C) (B) Figure S9: Simulation graphs of TRAF-6 crosstalk point in (A) TNF (B) CD14 (C) MAPK network
(B) (A) (D) (C) Figure S10: Simulation graphs of MKK3/6 crosstalk point in (A) TNF (B) CD14 (C) EGF (D) MAPK network
(A) (B) (C) (D) Figure S11: Simulation graphs of MKK4/7 crosstalk point in (A) TNF (B) CD14 (C) EGF (D) MAPK network
(A) (C) (B) Figure S12: Simulation graphs of PIP2 crosstalk point in (A) EGF (B) PI3K (C) MAPK network
Table S1: Mean path length, diameter and average paths for individual pathways Table S2: Statistics of the MAPK network
Table S4: Reactions having high sensitivity coefficient (Wi,j) values in the network