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10.1 Pre-Read Questions. Name 2 limitations to cell growth. How does DNA limit cell growth? Why is the ratio of surface area to volume important? Describe the process of cell division. Ch 10: Cell Growth and Division. 10.1: Cell Growth. Cells. Does not continue to grow bigger
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10.1 Pre-Read Questions • Name 2 limitations to cell growth. • How does DNA limit cell growth? • Why is the ratio of surface area to volume important? • Describe the process of cell division.
Ch 10: Cell Growth and Division 10.1: Cell Growth
Cells • Does not continue to grow bigger • Cells just continue to produce more cells
Limits to Cell Growth • 2 main reasons • Larger a cell becomes, the more demands the cell places on its DNA
Limits to Cell Growth • 2 main reasons 2. Cell has more trouble moving enough nutrients and wastes in and out of cell
Reason #1 DNA “overload” • DNA = information that controls a cell’s function • if cells grow, DNA does not make extra copies • DNA would not be able to serve the needs of the cell
Reason #2: Exchanging Materials • how fast materials leave or enter the cell depends on surface area • food and oxygen depend on cell volume
Ratio of Surface Area to Volume • as surface area increases, its volume increases at a faster rate
Ratio of Surface Area to Volume Consequence = cells have a more difficult time to move needed materials in and waste products out
Cell Division • how cells reproduce • one cell divides into 2 new cells • daughter cells
Cell Division before cell division - cell copies DNA • Each daughter cell gets own copy of DNA
10.2A 12 / 5 / 06
2 Stages • Mitosis = division of the cell nucleus • Cytokinesis = division of the cytoplasm
Mitosis • asexual • source of new cells
Chromosomes • carries the genetic information • consists of DNA • cells have specific number of chromosomes
Chromosome • not visible until cell division • replicated before cell division • chromosomes change form to chromatids
Chromatids • Separate from each other and go into daughter cells • attached at a centromere • located near the middle of the chromatids
Centromere Chromatid
Cell Cycle • cell reproduction • forms two daughter cells • in between period = interphase
Cell Cycle: 4 phases • consists of 4 phases • M phase = mitosis and cytokinesis • S phase = chromosome replication (S = synthesis) • G1 and G2 (G = gap) -- growth and activity
Interphase • 3 of the 4 phases occur • G1 • S phase • G2
G1 Phase • cell growing • increase in size and synthesize new proteins and organelles
S Phase • chromosome replication • proteins synthesized
G2 Phase • DNA replication complete at beginning • shortest phase
G2 Phase • organelles produced • prepare for cell division
10.2 Post Read Questions • Describe the 2 stages of cell division. • Draw a chromosome and label and describe its parts. • What are the different phases of interphase? Describe each one. • What is the cell cycle?
10.2 B 12 / 06 / 06
Interphase • In between periods of cell division • Cell growth and DNA replication occur
Prophase • first and longest phase (50%-60%) • chromosome becomes visible • centrioles take position on opposite sides of nucleus at the centrosome
Prophase • Centrioles lie in centrosome so they can organize the spindle • Spindle = fanlike microtubule structure that helps separate the chromosomes
Prophase • end = chromosomes coil and nuclear envelope break down
Metaphase • lasts only a few minutes • chromosomes line up across the center of the cell
Metaphase (cont) • microtubules connect the centromere of each chromosome to the two poles of the spindle
Anaphase • centromeres that join the sister chromatids split into individual chromosomes and are moved apart to opposite poles
Telophase • chromosomes become dense material • spindle breaks apart • nucleolus appears
Cytokinesis • Division of cytoplasm • usually occurs the same time as telophase • Animal Cell = cell membrane draw inward and pinched off • Plant cell = cell plate forms midway between the 2 nuclei; cell wall appears
T I P M A ROPHASE ETAPHASE NAPHASE ELOPHASE NTERPHASE
A B E C D Put the pictures in order
A B E C D ANSWER
Ch 10 Review Questions (Cont) • What is cytokinesis? When does it occur? • Compare how cytokinesis works between animal and plant cells. • Describe metaphase. • Describe anaphase. • If you were to look at a picture of telophase and anaphase, how can you distinguish the difference between the two?
10.3 12 / 7 / 06
Review: Cell Cycle • Preparing for Cell Division • INTERPHASE • G1 • S • G2
Review: Cell Cycle • Steps of Cell Division • Mitosis • Prophase • Metaphase • Anaphase • Telophase / Cytokinesis
Look at Figure 10.7 • Observe what is going on • What is happening in each step?
Cyclin • protein • regulates the timing of the cell cycle in eukaryotic cells
Regulatory Proteins • Two types • Internal Regulators • External Regulators
Internal Regulators • proteins that respond to events inside the cell • signals cell cycle to continue ONLY WHEN OTHER THINGS ARE COMPLETE