University of Colorado

1. University of Colorado is vital to Colorado’s Economy, Health, and Quality of Life

2. Boulder Campus • Five colleges and four schools offering 3,400 courses and 175 areas of study. • Received more than $260 million in sponsored awards in FY 2004.

3. Boulder Campus Research Expertise: Kristi Anseth – Tissue Engineering, Rational Design of Biomaterials Doug Gin – Liquid Crystal Engineering, Nanomaterials Marcelo Sousa – Crystal Structures of ArnA, Cystic Fibrosis Application Rob Batey and Jeff Kieft – RNA Purification for RNA Crystallization

4. Boulder Campus Research Expertise: Margaret Murnane and Henry Kapteyn – High Resolution Imaging Systems Natalie Ahn – Novel Gene Regulator of Cancer Cell Invasion Lin Chen – Crystal Structure of HDAC9/MEF2/DNA, Heart Disease Target Xuedong Liu – Skp2/Cks1 Binding Interface, Cancer Therapeutic Target

5. Boulder Campus Research Expertise: Kathy Rowlan – Flu Chip Min Han – Monomethyl Branched-Chain Fatty Acids, Roles in Development Ryan Gill – Metabolic Engineering, Genomics Ted Randolph – Supercritical Fluid Reaction Engineering Chris Bowman – Photopolymerization

6. Health Sciences Center • Recognized nationally for research, teaching and outreach programs. • Ranked 5th in NIH funding per capita among public university health sciences centers, receiving $300 million in FY 2004.

7. Health Sciences Center Research Expertise: Charles Dinarello – Infectious Diseases, IL-32 and IL-18BP William Arend – Rheumatology, IL-1B r, Kineret® John Carpenter – Pharmaceutical Sciences, Protein Drug Formulation Paul Wischmeyer – Heat Shock Proteins

8. Health Sciences Center Research Expertise: Robert Allen – Hematology, Homocysteine Biomarker, B-12 Formulations Charles McHenry – Microbiology, Pol II Holozymes Paul Bunn – Medical Oncology, EGFr Responsive Biomarkers Don Bellgrau – Immunology, Fas Ligand

9. Health Sciences Center

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11. Research Collaboration at Work Larry Hunter (HSC) and Robin Knight (Boulder) – Bioinformatics Rob Batey (Boulder) and Jeff Kieft (HSC) – RNA Purification for RNA Crystallization Mike Bristow (HSC) and Leslie Leinwand (Boulder) – Cardiology, Heart Failure

12. Serving the Needs of Colorado and the Region Colorado School of Public Health • Address shortage of trained specialists and need for public health leadership in Colorado • Collaboration among major regional public universities (CSU, UNC) and the Colorado Dept of Public Health and Environment Existing Schools of Public Health 2004 • Improve overall population’s health while increasing health care access for rural and minority populations

13. Colorado Springs Campus • One of the fastest growing universities in the nation. • Distinguished in space and electronics research. • Mutually supportive relationship with Northern Command and Air Force Academy.

14. Colorado Springs Campus

15. Colorado Springs Campus Research Expertise: Karen Newell – Bioenergetics Terry Boult – Biometrics Zbignew Celinski & Robert Camley – High Frequency Devices

16. CU Ranks at the Top • CU-Boulder was ranked the 11th best public academic university in the world and 9th best public university in the U.S. in The Economist • CU School of Pharmacy ranks 1st in the nation for NIH individual research grants for full-time PhD-level faculty New U.S. News & World Report rankings (a few of CU’s top ten): 1stin the nation - School of Nursing Pediatric Nurse Practitioner specialty in master’s program 5th - CU School of Medicine family medicine specialty 6th - Leeds School of Business Deming Center undergraduate entrepreneurship program among public institutions 6th - CU-Health Sciences Center Graduate School, Physician Assistant/Child Health Associate Program 6th - CU-Colorado Springs among public master’s universities in the West 6th - Nursing service administration specialty and 10th for the gerontological/geriatric specialty 7th - Community/public health for clinical nurse specialists 9th - School of Medicine among primary care medical schools

17. 2004 U.S. Professor of the YearCarl E. Wieman • CU-Boulder distinguished professor of physics and Nobel laureate • Named U.S. Professor of the Year among all doctoral and research universities in the U.S. • The award recognizes his unwavering dedication to undergraduate teaching

18. CU and Colorado’s Economy • For every $1 in unrestricted state general fund support • CU adds $16.64 to the CO economy (based on 2002 data) • $1.01 is recaptured by CO in taxes (one of the highest rates of return for any state university nationally) • CU brings back to the state $2.30 in competitive research grant funds (based on 2004 data) • CU students spent more than $742M in CO ($438M new money)

19. National Science Foundation Rankings* • Disciplines: • 3rd in physical sciences • 4th in environmental sciences • 7th in psychology • 7th in social sciences • 3rd largest increase in federal research dollars * 2002 data

20. Developing Industries in Colorado Space and Aeronautics • CU-Boulder #1 public university for NASA funding • $12.5 million CU-Boulder instrument orbiting Saturn on NASA's Cassini-Huygens spacecraft • $8.7 million CU-Boulder instrument is on NASA’s high-tech Mercury mission, may be involved with New Horizons Mission to Pluto • CU-Colorado Springs signs MOU with Air Force Space Command to establish a “national space university” • CU-Colorado Springs signs MOU with U.S. Northern Command • 17 CU alumni have become NASA astronauts

21. Developing Industries in Colorado Biotechnology • Colorado Bioscience Park Aurora at the Fitzsimons campus • 160 acres of space for research-oriented bioscience and biotechnology companies • Colorado Initiative in Molecular Biotechnology making Colorado’s Front Range a national powerhouse in the emerging field of genomics and molecular biotechnology

22. Developing Industries in Colorado Biotechnology Center for Pharmaceutical Biotechnologyis an industry-university research team to fast-track development of a botulism vaccine to use against bioterrorism CU Institute of Bioenergeticsstudies how cellular metabolism affects the immune system with the intention of treating diseases (e.g. cancer, diabetes)

23. CU Technology Transfer: Applying research to grow the economy • 177 active licenses, nearly one-third of which are held by Colorado companies • Added Children’s Hospital and Denver Health and Hospital Authority • 35 total active companies based on CU IP Companies include:Myogen, Westminster, Dharmacon, Lafayette: acquired by Fischer Scientific, Knowledge Analysis Technologies, Boulder, Amgen, Longmont and Boulder,CDM Optics, Inc., Boulder

24. CU Technology Transfer: Maximizing CU’s Research Potential Fiscal Year 2005 Activity • 180 Invention Disclosures • 60 Licensing Transactions • 10 Start-Up Companies • ~ $25 Million in Royalty Income

25. CU Discoveries and Clinical Trials

26. Boulder

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28. Colorado Springs

29. The University of Colorado Charging ahead