1 / 23

Heart Failure

Heart Failure. By:Dawit Ayele ( MD,Internist ). Definition. “ Heart (or cardiac) failure is the pathophysiological state in which the heart is unable to pump blood at a rate commensurate with the requirements of the metabolizing tissues or can do so only

vance
Download Presentation

Heart Failure

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript


  1. Heart Failure By:DawitAyele(MD,Internist)

  2. Definition • “Heart (or cardiac) failure is the pathophysiological state in which • the heart is unable to pump blood at a rate commensurate with • the requirements of the metabolizing tissues or can do so only • from an elevated filling pressure.” • - Eugene Braunwald • “Congestive heart failure (CHF) represents a complex clinical • syndrome characterized by abnormalities of left ventricular • function and neurohormonal regulation, which are accompanied • by effort intolerance, fluid retention, and reduced longevity” • - Milton Packer

  3. Heart Failure: Epidemiology 􀁺 Burden of CHF is staggering 􀁺 5 million in US (1.5% of all adults) 􀁺 500,000 cases annually 􀁺 In the elderly 􀁺 6-10% prevalence 􀁺 80% hospitalized with HF 􀁺 250,000 death/year attributable to CHF 􀁺 $38 billion (5.4% of healthcare cost)

  4. Underlying Etiologies • Alcohol-- • Diabetes— • Cardiomyopathies • Coronary artery disease- • HTN--both • Valvular heart disease (especially aorta and mitral disease)--chronic • Congenital

  5. Precepitating factors • Infection • Arrhythmia • Physical,Fluid,Dietary,Env’tal,Emotional excess • MI • Anemia • Pulmonary embolism • Worsening of HTN • Thyrotoxicosis • Infective endocarditis • Rheumatic,viral or other myocarditis..

  6. Forms of Heart Failure • SYSTOLIC VERSUS DIASTOLIC FAILURE • LOW-OUTPUT VERSUS HIGH-OUTPUT HEART FAILURE • ACUTE VERSUS CHRONIC HEART FAILURE • RIGHT-SIDED VERSUS LEFT-SIDED HEART FAILURE • BACKWARD VERSUS FORWARD HEART FAILURE

  7. Typical presentations of heart failure • 1. Syndrome of decrease exercise tolerance • 2. Syndrome of fluid retention • 3. No symptoms but incidental discovery of LV • dysfunction

  8. Heart Failure is a Clinical Diagnosis • 􀁺 Minor Criteria • 􀁺 Ankle edema • 􀁺 Night cough • 􀁺 Exertionaldyspnea • 􀁺 Hepatomegaly • 􀁺 Pleural effusion • 􀁺 Tachycardia (>120) • 􀁺 Decrease VC • 􀁺 Weight loss with CHF tx • Framingham Criteria • Major Criteria • 􀁺 Orthopnea/PND • 􀁺 Venous distension • 􀁺 Rales • 􀁺 Cardiomegaly • 􀁺 Acute pulm edema • 􀁺 Elevated JVP • 􀁺 HJR • 􀁺 Circ time >25s

  9. NYHA Class 􀁺 • Class I: Symptoms with more than ordinary activity • Class II: Symptoms with ordinary activity • Class III: Symptoms with minimal activity • Class IIIa: No dyspnea at rest • Class IIIb: Recent dyspnea at rest • Class IV: Symptoms at rest

  10. Stages of Heart Failure At Risk for Heart Failure: STAGE A High risk for developing HF • STAGE B Asymptomatic LV dysfunction • Heart Failure: • STAGE C Past or current symptoms of HF • STAGE D End-stage HF

  11. Stages of Heart Failure • Designed to emphasize preventability of HF • Designed to recognize the progressive nature of LV dysfunction

  12. Stages of Heart Failure • COMPLEMENT, DO NOT REPLACE NYHA CLASSES • NYHA Classes - shift back/forth in individual patient (in response to Rx and/or progression of disease) • Stages - progress in one direction due to cardiac remodeling

  13. Left Ventricular Failure with PE • When pressure becomes too high, the fluid portion of the blood is forced into the alveoli. • decreased oxygenation capacity of the lungs • AMI common with LVF, suspect • Occurs when the left ventricle fails as an effective forward pump • back pressure of blood into the pulmonary circulation •  pulmonary edema • Cannot eject all of the blood delivered from the right heart. • Left atrial pressure rises  increased pressure in the pulmonary veins and capillaries

  14. Signs and Symptoms of LVF • Diaphoresis— • Results from sympathetic stimulation • Pulmonary congestion • Often present • Rales—especially at the bases. • Rhonchi—associated with fluid in the larger airways indicative of severe failure • Wheezes—response to airway spasm • Severe resp. distress– • Evidenced by orthopnea, dyspnea • Hx of paroxysmal nocturnal dyspnea. • Severe apprehension, agitation, confusion— • Resulting from hypoxia • Feels like he/she is smothering • Cyanosis—

  15. Jugular Venous Distention—not directly related to LVF. • Comes from back pressure building from right heart into venous circulation • Vital Signs— • Significant increase in sympathetic discharge to compensate. • BP—elevated • Pulse rate—elevated to compensate for decreased stroke volume. • Respirations—rapid and labored

  16. Compensatory Mechanisms in CHF • Neurohormonalsystem • Renin-angiotensin-aldosteronesystem • Ventricular hypertrophy

  17. Neurohormonal Activation Contributes to the Progression of CHF Myocardial Disease Impedance LV Dysfunction LV RemodelingVascular Remodeling Vasoconstriction Neurohormonal Activation Renal Blood Flow Preload Na Retention

  18. Renin-Angiotensin Mechanism • Decreased renal blood flow secondary to low cardiac output triggers renin secretion by the kidneys • Aldosterone is released  increase in Na+ retention  water retention • Preload increases • Worsening failure

  19. Ventricular Hypertrophy • Long term compensatory mechanism • Increases in size due to increase in work load ie skeletal muscle

  20. Patient approach & Mgt • Principles:thoroughHx & P/E • Supplemental investigations especially:BNP,ECG,Echocardiography,CXR • Management:(1) general measures; (2) correction of the underlying cause; (3) removal of the precipitating cause; (4) prevention of deterioration of cardiac function; and (5) control of the congestive HF state

  21. Heart Failure: Disease Management Control Volume Slow Disease Progression + Diuretic RAAS Inhibition Beta-Blockade Treat residual symptoms DIGOXIN SPIRONOLACTONE Am J Cardiol 1999;83(suppl 2A):9A-38A

More Related