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Microbiology 1 (MICR V01) Summer 2010 Sec. 50284 Lecture: Dr. Marta D. de Jesus (Ph.D.)

Microbiology 1 (MICR V01) Summer 2010 Sec. 50284 Lecture: Dr. Marta D. de Jesus (Ph.D.) TuWTh 3:00 - 5:50 PM (SCI-313) Lab: Prof. Eden Bellenson TuWTh 12:00 - 2:50 PM (SCI-311) Please pick up all handouts. Introduction What is MICR V01? Nuts & bolts Roll Syllabus Comments

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Microbiology 1 (MICR V01) Summer 2010 Sec. 50284 Lecture: Dr. Marta D. de Jesus (Ph.D.)

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  1. Microbiology 1 (MICR V01) Summer 2010 Sec. 50284 Lecture: Dr. Marta D. de Jesus (Ph.D.) TuWTh 3:00 - 5:50 PM (SCI-313) Lab: Prof. Eden Bellenson TuWTh12:00 - 2:50 PM (SCI-311) Please pick up all handouts.

  2. Introduction What is MICR V01? Nuts & bolts Roll Syllabus Comments Helps & Hints

  3. College Website http://www.venturacollege.edu Your District Website: http://my.vcccd.edu

  4. Course Syllabus A. COURSE DESCRIPTION B. METHOD OF INSTRUCTION C. STUDENT LEARNING OBJECTIVES D. COURSE OBJECTIVES E. COURSE TOPICS/UNITS F. CORE COMPETENCIES G. TEXTBOOK(S) AND REQUIRED SUPPLIES

  5. Who is this class for? Nursing: RN and beyond (BSN, MSN, PhD) other pre-health: PharmD, OD, PA, etc. (possibly DVM) other interests (bioengineering, chemical engineering, biotechnology, etc.) Note: not usually recommended for MD or DO (not accepted as units by medical schools in general) or Microbiology majors.

  6. Pre-requisites for Microbiology CHEM V20 & V20L/V30 or V30 L/V 01 & V01L(requires beg. algebra)AND PHSO V01(requires ANAT V01 which requires BIOLV 01 & V01L)or BIOL V04 What topics did you get from those courses that you will use here? Scientific method Metric system & conversions Subatomic particles, periodic table, element descriptions , chemical symbols & formulas Acids, bases/alkalis & buffers Basic microscopy Prokaryotic & eukaryotic cells (plant & animal) Cell division Biological molecules (carbohydrates, lipids, proteins, nucleic acids) Basic enzyme function DNA replication, RNA transcription & protein synthesis Glycolysis, aerobic respiration, photosynthesis Basic taxonomy Human anatomy & physiology (including an intro to the immune system) If you don’t remember or are shaky on a number of these, this class will be very difficult.

  7. Textbook Also available: 1) CD-ROM & access to microbiologyplace website (comes with new texts or go to publisher website to purchase) 2) Study Guide (optional)

  8. Course Syllabus H. GRADING PLAN (p3) (lecture %).75 + (lab %).25 = final % Guaranteed grades 90-100% -> A 80-89% -> B 70-79% -> C 60-69% -> D Below -> F

  9. Course Syllabus I. COURSE COMPONENT SPECIFICS Quizzes: 10% (daily) Lecture Tests: 40% (weekly) Lecture Final: 25% Please sit in the front half of the classroom for these Lab: 25%

  10. For Tests: 883 For Quizzes: 815

  11. For Final Exam: 886

  12. Course Syllabus J. CLASSROOM RULES OF CONDUCT http://www.venturacollege.edu/honesty/ 1) Academic Dishonesty 2) Disruption/Obstruction of class K. Some of the On-Campus Student Help pg 29 & 49 Sched. Of Classes http://www.assist.org L. EMERGENCY PROCEDURES

  13. Course Syllabus M. Other miscellaneous helps DISCLAIMER Bloom’s Taxonomy (types of questions on college exams) p7 N. PLANNED SCHEDULE AFFIDAVIT & Student Information Sheet - due tomorrow

  14. Introduction What is MICR V01? Nuts & bolts Roll Syllabus Comments Helps & Hints

  15. Learning preferences/styles - 4 popular models So what works? Everyone can/does use these different modes VA(R)K (sensory) Sternberg Kolb

  16. Dale’s Cone of Experience- the more you’re involved, the more you get

  17. Guaranteed: S+Q+3R+P Method of Studying Survey Question Read Recite Review Practice Hitch?

  18. Introduction What is Microbiology?

  19. Microbes are: 1. small

  20. Microbes are: 1. small

  21. Microbes are: 1. small 16,600x (when image is 2 in x 2 in)

  22. Microbes are: 1. small 2. ubiquitous

  23. Microbes are: 1. small 2. ubiquitous 3. ecologically important

  24. Microbes are: 1. small 2. ubiquitous 3. ecologically important 4. medically important antibiotics trypanosomes

  25. Microbes are: 1. small 2. ubiquitous 3. ecologically important 4. medically important 5. economically important

  26. Microbes are: 1. small 2. ubiquitous 3. ecologically important 4. medically important 5. economically important 6. often beneficial probiotics bioremediation

  27. (All kingdoms except plants) (algology) (More general: protistology) (molecular biology) & microbial ecology

  28. What is Science? sciens (Latin) 1. process/method

  29. What is Science? sciens (Latin) 1. process/method 2. information

  30. What is not Science? examples Art Literature Philosophy Theology/Religion (and some subjects are in between…)

  31. Scientific Method

  32. In every experiment should have 2 groups: • experimental control In lab, sometimes have 2 kinds of controls: positive negative

  33. Big Moments in the History of Microbiology Diseases & microbes 1. ancient explanations, transmission 2. fermentation 3. spontaneous generation disproved (Aristotle, Redi, Needham, Spallanzani, Pasteur) 4. (in)famous diseases a. Plague of Athens (430-25 B.C.E) b. Black Plague (1348- outbreaks until 16th Cent. ) c. syphilis (~1500?) d. Spanish Flu (1918) e. HIV -> AIDS (late 20th Cent.-?)

  34. People from text (before 1850) Robert Hooke (1665) Antoni von Leeuwenhoek (1674) Francesco Redi (1668) Carolus Linnaeus (= Carl von Linne; 1735) John Needham (1745) Lazzaro Spallanzani (1765) Edward Jenner (1789) Theodor Schwann & Matthei Schleiden (1839) Ignaz Semmelweiss (1844) After ~1855: Golden Age of Microbiology (some say 1857-1914)

  35. Florence Nightingale (1854-6) Walter Reed (1900) • John Snow (1854) Paul Ehrlich (1908) • Rudolf Virchow (1858) Emil von Behring & Shibasaburo Kitasato • *Louis Pasteur (1857)* Albert Kluyver & C. B. van Niel • Sergei Winogradsky (1885-8) Alexander Fleming (1928) • Eduard Buchner (1897) Gerhard Domagk (1935) • Joseph Lister (1865) Oswald Avery/Colin MacLeod/Maclyn McCarty (1944) • *Robert Koch (1876)* George Beadle & Edward Tatum (1958) • Charles Laveran (1880) Linus Pauling (1965) • Christian Gram (1884) Carl Woese (1977) • Julius Richard Petri (1887) • Dmitri Iwanoski (1892) • Martinus Beijerink (1898) http://www.microbeworld.org/index.php?option=com_content&view=category&layout=blog&id=64&Itemid=61

  36. The 1950’s: electron microscopes TEM SEM

  37. Emerging & re-emerging infectious diseases (EIDs) http://www.niaid.nih.gov/topics/emerging/pages/list.aspx

  38. Are we in the 2nd Golden Age of Microbiology? Many say “yes” - Most of modern biotechnology uses microbiology or techniques first developed with microbes. - We know more about microbes now than ever before & the information is accelerating… Example: We now know the entire DNA coding for more than many different bacterial species & more are being added all the time. The first bacteria to be completely DNA sequenced was Haemophilus influenzae (1995, after many years of work). We now have labs that complete equivalent work in a few months (note: making a vaccine or drug takes far, far longer).

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