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CANCER RISKS FROM ARSENIC IN DRINKING WATER

Seminar On World Wide Danger of Arsenic Poisoning in Water and Sustainable Solutions Organized by Academy of Healthy water, Ecosystem and Environment Derby, Kansas, USA. CANCER RISKS FROM ARSENIC IN DRINKING WATER. Environmental exposures. C ancer risks: Tobacco smoke Radon in homes

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CANCER RISKS FROM ARSENIC IN DRINKING WATER

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  1. Seminar On World Wide Danger of Arsenic Poisoning in Water and Sustainable SolutionsOrganized byAcademy of Healthy water, Ecosystem and EnvironmentDerby, Kansas, USA

  2. CANCER RISKS FROM ARSENIC IN DRINKING WATER

  3. Environmental exposures • Cancer risks: • Tobacco smoke • Radon in homes • Arsenic

  4. Lifetime risks of dying from cancer due to environmental exposures • Tobacco smoke: • Low exposure = 4/1000 • High exposure =10/1000 • Radon in homes: • Average exposure = 3/1000 • High exposure =20/1000 • Arsenic in drinking water: • U.S. estimated average = 1/1000 • U.S. water standard = 21/1000

  5. ARSINIC • Organic form • Inorganic forms • More toxic

  6. Drinking water contaminated with Arsenic • Skin • Lung • Liver • Kidney • Other organs

  7. SKIN CANCER • First described in 1888 in patients treated with arsenical mixtures for skin conditions • Arsenic from water supplies and drugs is known to cause skin cancer • Prevalence among highly exposed males aged >60 reached 25%

  8. Liver cancer • Liver Cancer • Angiosarcoma • Supported by a series of case reports • Winegrowers in Germany • Taiwan

  9. Lung Cancer • Ingestion: • Water supplies • Comparable to tobacco smoke and radon • Inhalation: • Smelters

  10. Kidney and Bladder Cancer • There is a clear relationship between arsenic water levels and bladder and kidney cancer

  11. CONCLUSION Arsenic is a human carcinogen • Results from epidemiological studies, showed persuasive evidence that inorganic arsenic is a cause of human cancer at several sites. • There is strong evidence supporting a causal relationship between ingested arsenic and cancer of skin, liver, lung cancer. • There is some evidence from Taiwan supporting a causal relationship between ingested arsenic and cancer of kidney and bladder cancer.

  12. Is Arsenic Useful? • Industry • Medicine • Leukemia (Arsenic Trioxide, Trisenox) • Autoimmune diseases

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