The Urinary System

1. The Urinary System

2. Functions of the Urinary system: • Removes salts and nitrogenous wastes • Maintains normal amounts of water and electrolytes • Regulates the pH level and volume of fluids. • Helps control red blood cell production and blood pressure.

3. The organs of the Urinary System: • The Kidney (2 of them) • And all of the accessory organs with the kidney • A pair of ureters (tube structures) • Urinary bladder • Urethra (tube structure)

4. They Kidney • Reddish brown bean shaped organ that is smooth. • They lie on both sides of the vertebral column on the upper posterior wall of the abdominal. • The kidney attaches to blood vessels and lymphatic vessels from the cardiovascular system at the renal pelvis.

5. They Kidney

6. They Kidney • Let’s label the parts of the kidney!

7. Answer Key: Kidney Label • Renal pyramid • Interlobar artery • Renal artery • Renal vein • Renal hylum • Renal pelvis • Ureter • Minor calyx Renal capsule Inferior renal capsule Superior renal capsule Interlobar vein Nephron Minor calyx Major calyx Renal papilla Renal column

8. The role of the kidney: • Helps maintain homeostasis by removing wastes from the blood and combining them with excess water and electrolytes to form urine which eventually gets excreted. • Help control the rate of red blood cell production through a hormone they secrete. • Help maintain blood pressure • Play a role in the activation of Vitamin D

9. The role of the kidney: • Lined with blood vessels. • Recieves oxygenated blood through the Abdominal Aorta. This branches to interlobar arterioles, and finally small capillaries called glomerulus located on the nephron (where urine is formed and processed). • Deoxygenated blood leaves the kidneys through the Inferior Vena Cave to be returned to the heart.

10. The Ureters • A tube about 25cm long • Begins at the renal pelvis of the kidney and runs parallel to the vertebral column on each side until it reaches the urinary bladder. • Made up of mucous lining, smooth muscle and connective tissue. • What do you think the smooth muscle does?

11. The Ureters • Your ureters have a valve just like the heart to prevent the flow of urine back through the ureters. • This valve called: ureteral mucous opening, opens when urine is pushed against it and closes when urine reaches the bladder. Correct- they propel the urine to your bladder!

12. The Bladder • A hallow, muscular organ, spherical shape, very flexible, located in the pelvic cavity. • Do you remember what type of tissues it is made up of? • Transitional Epithelium Tissue!! • It is also made up of smooth muscle, mucous membranes, and connective tissues (elastic).

13. The Bladder • At the triangular portion it attaches to the urethra tube. Label the structure of the bladder:

14. The Bladder • What is the difference between the Internal urethral sphincter and the external urethral sphincter? • The internal urethral sphincter is a smooth muscle. Which means what? • Does it automatically. You can not control when urine wants to leave the bladder. • The external is a skeletal muscle. You can control though if you release urine from the urethra. • You are able to “hold it” like when I don’t give you a pass to the bathroom- your external urethral sphincter muscles are working.

15. The Urethra • The tube that transports urine from the urinary bladder to outside the body. • Contains glands that secrete mucous into the tube to help urine pass.

16. URINE FORMATION: The Nephron

17. Filtration Filtration Filtration Filtration Figure 3. Urine formation takes place in the nephron (Functional unit of the kidney).

18. Structure of the Nephron:

19. Urine production • Urine formation begins with the process of filtration of blood, which goes on continually in the renal corpuscles • As blood flows through the glomeruli (capillaries), much of its fluid, containing both useful chemicals and waste materials, soaks out of the blood through the membranes (by osmosis and diffusion) where it is filtered and then flows into the Bowman's capsule (The next spot on the nephron).

20. This process is called glomerular filtration. • water, excess salts (primarily Na+ and K+), glucose, and waste products of the body are called urea • Urea is formed in the body to eliminate toxic ammonia products that are formed in the liver from amino acids

21. WHAT IS EXCRETED??? • About 125 ml of water and dissolved substances are filtered out of the blood per minute. After waste or water is excreted, it can also be REABSORBED. • Reabsorption, by definition, is the movement of substances out of the blood into the renal tubules then back into the blood capillaries located around the tubules • Substances reabsorbed are water, glucose and other nutrients, and sodium (Na+) and other ions

22. The pathway of urine: Excretion and reabsorption next goes in the proximal convoluted tubules and continues in the loop of Henle, distal convoluted tubules, and collecting tubules

26. Substances secreted and removed are hydrogen ions (H+), potassium ions (K+), ammonia (NH3), and certain drugs • Kidney tubule secretion plays a crucial role in maintaining the body's acid-base balance, another important body function that the kidney participates in.

27. Control of Urine Production • Urine is produced not only in order to eliminate many of the cellular waste products, but also to control both the amount and the composition of the extracellular fluid in the body • The kidney tubule regulation of the salt and water in our bodies is the most important factor in determining urine volume.

28. The level of water and salts excreted in urine - the urine volume - is adjusted to the needs of the body. As a general rule, however, and under optimum conditions, the body produces urine at a rate of about 1 ml/min. • Controlled by hormones, chemical messengers that travel through the blood system and act as regulators of many of the body's internal activities

29. Control of Urine Volume through ADH (anti-diuretic hormone ) • Diuretic is a substance that acts to increase urine production • feeling "bloated" = retaining water • An anti- diuretic, on the other hand, is a chemical that inhibits urine formation • ADH produces its anti-diuretic effect by acting on the kidneys and causing them to reduce the amount of water they excrete

30. ADH is important in regulating the water concentration of body fluids, which ultimately helps to maintain an appropriate sodium concentration in the body • The sodium concentration in the fluid is the factor that either stimulates the pituitary to release ADH or to inhibit the release of ADH

31. Figure 5. The regulation of body water and sodium ion (Na+) concentration in the blood is controlled through the release of anti-diuretic hormone (ADH). This system operates using a negative feedback loop.

32. For this reason, ADH is described as the "water-retaining hormone." You might also think of it as the "urine-decreasing hormone." • When a person drinks an excess of water, the sodium in the body fluids, including the blood becomes more dilute and the release of ADH is inhibited. • The kidneys excrete more watery urine until the water concentration of the body fluids returns to normal