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Parkinson’s Disease. By: Maryam Nabihah binti Hajah Mustafa Azila Ariffin. What is Parkinson’s Disease?. second most common neurodegenerative disorder progressive loss of muscle control trembling of the limbs and head while at rest stiffness, slowness, and impaired balance.
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Parkinson’s Disease By: Maryam NabihahbintiHajah Mustafa AzilaAriffin
What is Parkinson’s Disease? • second most common neurodegenerative disorder • progressive loss of muscle control • trembling of the limbs and head while at rest • stiffness, slowness, and impaired balance. • may become difficult to walk, talk, and complete simple tasks.
What causes PD? degenerative disorder of the CNS SubstantiaNigra (SN) controls movement Cells die in SN (pars compacta) stops producing Dopamine Loss in muscle control Thalamus and Globus PalidusInterna became overly active
Primary Symptoms • Tremor at rest • Bradykinesia • Impaired balance and coordination • Muscle rigidity • Stooped posture • Expressionless face • Decreased sense of smell
Problems with advancing Parkinson’s Disease • Constipation • Urinary problems • Orthostatic hypotension • Dysphagia • Excessive salivation • Pains • Autonomic Impairment • Motor complications • Dyskinesia • No response • Dystonia
Classifications • Idiopathic • Acquired • Hereditary parkinsonism • Parkinson plus syndrome
Treatment • Drug treatment (levodopa, dopamine agonists, MAO-B inhibitors) • Therapy (occupational, speech and language, physiotherapy) • Surgery- Deep brain stimulation
Other Related Diseases • Lewy Body Dementia • Progressive Supranuclear Palsy • Normal Pressure Hydrocephalus • Shy-Drager Syndrome
Parkinson In Malaysia • Lloyd Tan Parkinson’s Trust Fund • Malaysian’s Parkinson’s Disease Association • World Parkinson’s Disease day • Background • Gender • Age
Sources • http://www.ncbi.nlm.nih.gov/pubmed/21448542 • http://emedicine.medscape.com/article/1831191-overview • http://en.wikipedia.org/wiki/Parkinson's_disease#cite_note-Jankovic2008-0 • http://www.pdmdcenter.com/articles/HopkinsWeb/index.html • http://www.lloydtan-trust.com/ • http://www.nlm.nih.gov/medlineplus/parkinsonsdisease.html#cat57 • http://parkinsons-disease.emedtv.com/parkinson's-disease/natural-cure-for-parkinson's-disease.html