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E. coli Asp AT

E. coli Asp AT. Provides specificity by binding γ -COO -. Holds C- α -COO - (prevents decarboxylation), also prevents racemization. Where C- α proton would have been. Lysine that acts as PLP “holder” and suspected base in C- α H + removal. Planar PLP, side on.

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E. coli Asp AT

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  1. E. coli Asp AT

  2. Provides specificity by binding γ-COO- Holds C-α -COO- (prevents decarboxylation), also prevents racemization Where C- α proton would have been Lysine that acts as PLP “holder” and suspected base in C-α H+ removal Planar PLP, side on Tyrosine that helps Lys act as general base

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