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Comprehensive Organic Chemistry II Course Overview

Welcome to Dr. Tim Schoof's Organic Chemistry II course, covering Alkenes, Alkynes, Addition Reactions, Radical Reactions, Spectroscopy, Alcohols, Ethers, Carbonyl Compounds, Conjugated Systems, Aromatic Compounds, Electrophilic Aromatic Substitution, and more.

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Comprehensive Organic Chemistry II Course Overview

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  1. Organic Chemistry II W e l c o m e

  2. Dr. Tim Schoof Instructor / Host

  3. Course Outline • Introduction • Review of Major Concepts in Organic I • Alkenes & Alkynes (Chapter 7) • Physical Properties of Alkenes & Alkynes • E-Z System • Relative Stabilities of Alkenes & Cycloalkenes • Zaitsev’s Rule & Hofmann Rule

  4. Course Outline Cont. • Alkenes & Alkynes (Chapter 7) • Dehydration of Alcohols • Vicinal (Vic) & Geminal (Gem) • Terminal Alkynes • Hydrogenation of Alkenes • Syn & Anti Additions • Index of Hydrogen Deficiency

  5. Course Outline Cont. • Addition Reactions (Chapter 8) • Mechanism • Markovnikov’s Rule • Acid-Catalyzed Hydration • Variations • Oxidative Cleavage of Alkenes

  6. Course Outline Cont. • Radical Reactions (Chapter 10) • Description • Importance in Biology, Medicine & Industry • Mechanism • Selectivity of Halogens • Anti-Markovnikov Reaction • Ozone Depletion & CFC’s • Test 1

  7. Course Outline Cont. • Spectroscopy (Chapters 9, 2, 13) • Electromagnetic Spectrum • General Principle • Infrared Spectroscopy (Chapter 2) • Ultraviolet Spectroscopy (Chapter 13) • NMR Spectroscopy (Chapter 9) • MRI Spectroscopy (Chapter 9) • Structural Analysis

  8. Course Outline Cont. • Alcohols & Ethers (Chapter 11) • Important Alcohols & Ethers • Physical Properties • Synthesis of Alcohols form Alkenes • Dehydration Synthesis (Condensation) • Phase-Transfer Catalysis

  9. Course Outline Cont. • Carbonyl Compounds (Chapter 12) • Carbonyl Containing Compounds • Nucleophilic Addition Reactions • Oxidation-Reduction (Redox) Reactions • Organometallic (Grignard Reagents) Note: overview only • Test 2

  10. Course Outline Cont. • Conjugated Systems (Chapter 13) • Classification • Resonance Review • Stability of Conjugated Dienes • Kinetic vs. Thermodynamic Control

  11. Course Outline Cont. • Aromatic Compounds (Chapter 14) • Aliphatic vs. Aromatic • Nomenclature • Ortho, Meta, Para • Annulenes • Stability • Aromatic • Antiaromatic • Nonaromatic) • Huckel’s Rule

  12. Course Outline Cont. • Aromatic Compounds (Chapter 14) • Heterocyclic Aromatic Compounds • Aromatic Compounds in Biochemistry • Energy Transport

  13. Course Outline Cont. • Electrophilic Aromatic Substitution Reactions (Chapter 15) • General Mechanism • Specific Examples • Effect of Substituents • Activators • Deactivators • Ortho-Para Directors • Meta Directors • Reaction Scenarios

  14. Course Outline Cont. • Odds & Ends • Reactivity of Aldehydes & Ketones • Hemiacetals & Hemiketals • Enol • Tautomers • Carboxylic Acid Derivatives • Decarboxylation • Thio Group

  15. Course Outline Cont. • Odds & Ends Cont. • Amines vs. Amides • Biologically Important Amines • Chemotherapy • Biochemistry Prep. (Glycolysis) • Test 3

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