150 likes | 220 Views
Organic Chemistry II. W e l c o m e. Dr. Tim Schoof. Instructor / Host. Course Outline. Introduction Review of Major Concepts in Organic I Alkenes & Alkynes (Chapter 7) Physical Properties of Alkenes & Alkynes E-Z System Relative Stabilities of Alkenes & Cycloalkenes
E N D
Organic Chemistry II W e l c o m e
Dr. Tim Schoof Instructor / Host
Course Outline • Introduction • Review of Major Concepts in Organic I • Alkenes & Alkynes (Chapter 7) • Physical Properties of Alkenes & Alkynes • E-Z System • Relative Stabilities of Alkenes & Cycloalkenes • Zaitsev’s Rule & Hofmann Rule
Course Outline Cont. • Alkenes & Alkynes (Chapter 7) • Dehydration of Alcohols • Vicinal (Vic) & Geminal (Gem) • Terminal Alkynes • Hydrogenation of Alkenes • Syn & Anti Additions • Index of Hydrogen Deficiency
Course Outline Cont. • Addition Reactions (Chapter 8) • Mechanism • Markovnikov’s Rule • Acid-Catalyzed Hydration • Variations • Oxidative Cleavage of Alkenes
Course Outline Cont. • Radical Reactions (Chapter 10) • Description • Importance in Biology, Medicine & Industry • Mechanism • Selectivity of Halogens • Anti-Markovnikov Reaction • Ozone Depletion & CFC’s • Test 1
Course Outline Cont. • Spectroscopy (Chapters 9, 2, 13) • Electromagnetic Spectrum • General Principle • Infrared Spectroscopy (Chapter 2) • Ultraviolet Spectroscopy (Chapter 13) • NMR Spectroscopy (Chapter 9) • MRI Spectroscopy (Chapter 9) • Structural Analysis
Course Outline Cont. • Alcohols & Ethers (Chapter 11) • Important Alcohols & Ethers • Physical Properties • Synthesis of Alcohols form Alkenes • Dehydration Synthesis (Condensation) • Phase-Transfer Catalysis
Course Outline Cont. • Carbonyl Compounds (Chapter 12) • Carbonyl Containing Compounds • Nucleophilic Addition Reactions • Oxidation-Reduction (Redox) Reactions • Organometallic (Grignard Reagents) Note: overview only • Test 2
Course Outline Cont. • Conjugated Systems (Chapter 13) • Classification • Resonance Review • Stability of Conjugated Dienes • Kinetic vs. Thermodynamic Control
Course Outline Cont. • Aromatic Compounds (Chapter 14) • Aliphatic vs. Aromatic • Nomenclature • Ortho, Meta, Para • Annulenes • Stability • Aromatic • Antiaromatic • Nonaromatic) • Huckel’s Rule
Course Outline Cont. • Aromatic Compounds (Chapter 14) • Heterocyclic Aromatic Compounds • Aromatic Compounds in Biochemistry • Energy Transport
Course Outline Cont. • Electrophilic Aromatic Substitution Reactions (Chapter 15) • General Mechanism • Specific Examples • Effect of Substituents • Activators • Deactivators • Ortho-Para Directors • Meta Directors • Reaction Scenarios
Course Outline Cont. • Odds & Ends • Reactivity of Aldehydes & Ketones • Hemiacetals & Hemiketals • Enol • Tautomers • Carboxylic Acid Derivatives • Decarboxylation • Thio Group
Course Outline Cont. • Odds & Ends Cont. • Amines vs. Amides • Biologically Important Amines • Chemotherapy • Biochemistry Prep. (Glycolysis) • Test 3