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Explore the latest research on visual field changes in glaucoma, how they relate to retinal nerve fiber layer (RNFL) loss, and the importance of structural and functional tests in early detection and monitoring of the disease.
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Visual field examination, is it time to say goodbye? Aharon Wegner awegner@yahoo.com Glaucoma Service, Department of Ophthalmology, Klinikum rechts der Isar, Technical University Munich 22 Ismaninger St, 81675 Munich awegner@yahoo.com
Visual field changes translated to ganglion cell loss Not only, that a loss of 25%-30% of RNFL is needed before we notice a visual field loss, the logarithmic presentation caches the amount of the damage. Adapted according to: Garway–Heath DF, Caprioli J, Fitzke FW, Hitchings RA. Scaling the Hill of Vision: The Physiological Relationship between Light Sensitivity and Ganglion Cell Numbers. Invest Ophthalmol Vis Sci. 2000;41:1774 –1782. awegner@yahoo.com
Relation between visual field to RNFL RNFL can be related to optic disc and visual field Ferreras A, Pablo LE, Garway-Heath DF, Fogagnolo P, García-Feijoo J. Mapping standard automated perimetry to the peripapillary retinal nerve fiber layer in glaucoma. Invest Ophthalmol Vis Sci. 2008;49:3018-25. awegner@yahoo.com
Relation between OCT print-out to RNFL RNFL can be related to optic disc and visual field Hood DC, Kardon RH. A framework for comparing structural and functional measures of glaucomatous damage. Prog Retin Eye Res. 2007;26:688-710. awegner@yahoo.com
Correlation between RNFL and visual field – a model The linear model’s predicted change in RNFL thickness with changes in SAP field loss express on log-linear coordinates. Hood DC, Kardon RH. A framework for comparing structural and functional measures of glaucomatous damage. Prog Retin Eye Res. 2007;26:688–710. awegner@yahoo.com
Correlation between RNFL and visual field Hood DC, Anderson SC, Wall M, Raza AS, Kardon RH. A Test of a Linear Model of Glaucomatous Structure–Function Loss Reveals Sources of Variability in Retinal Nerve Fiber and Visual Field Measurements. Invest Ophthalmol Vis Sci. 2009;50:4254–4266. awegner@yahoo.com
Structural tests detect earlier the damage and are more sensitive to progression at the initial stages of Glaucoma. Functional test can better detect a progression at the late stages of Glaucoma. awegner@yahoo.com