1 / 41

Introduction the Endocrine System

Introduction the Endocrine System. Chapter 7. What is a endocrine?. We divide endocrines into 3 groups. Steroid hormones Peptide hormones Amine hormones. Steroids. The Adrenal Gland: one source of steroids. All contain the cholesterol backbone. Notice how similar estrogen is to cortisol.

weston
Download Presentation

Introduction the Endocrine System

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript

  1. Introduction the Endocrine System Chapter 7

  2. What is a endocrine?

  3. We divide endocrines into 3 groups • Steroid hormones • Peptide hormones • Amine hormones

  4. Steroids

  5. The Adrenal Gland: one source of steroids

  6. All contain the cholesterol backbone

  7. Notice how similar estrogen is to cortisol

  8. Amines

  9. Amines as hormones: modified amino acids

  10. Pre-pro-hormone to Active hormone

  11. →Pituitary →Hypothalamus Pineal gland Thyroid Parathyroid Thymus Heart liver Stomach and intestine Pancreas Adrenal gland Kidney Testes Ovaries Adipose placenta Endocrine System: Wow!

  12. Hypothalamus and pituitary

  13. The protein hormones of these glands

  14. Control of Hormone Release

  15. 1. Hypothalamic Control of Anterior Pituitary

  16. 1a. Most endocrines are controlled by • Trophic factors

  17. 1b. A few endocrines are controlled by inhibition • Somatostatin • PIF

  18. 2. Hormone Secretions can be controlled by • Positive feedback • Negative feedback

  19. Negative Feedback Control

  20. Positive Feedback Control

  21. Feedback can be: • Short Loop Feedback • Long Loop Feedback

  22. Long Loop Feedback Short Loop

  23. Interactive affect of multiple hormones • Synergism • Permissiveness • Antagonism

  24. Pathologies • Diabetes MellitusType I • Diabetes Inspidius • Hyperthyroidism • Graves Disease • Hypothyroidism • Cushings Disease: secondary hypersecretion • Addison’s Disease: primary hyposecretion

  25. Pancreas and Insulin

  26. Diabetes Mellitus Type I Insulin deficiency Type II Non-responsive to insulin

  27. CUSHING DISEASE

  28. Cushing Disease • Excess gluconeogenesis: hyperglycemia • Muscle breakdown • Lipolysis • Paradox: central weight gain

  29. Cushing and its treatment

  30. Addison’s Disease

  31. Goiter: Enlarged Thyroid Gland

  32. Exophthalmus

  33. Primary hypersecretion at “final” site

  34. Secondary Hypersecretion: at pituitary level

  35. Secondary Hypersecretion at hypothalamic level

More Related