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Kearns-Sayre Syndrome. By Tommy Antony. Mitochondrial DNA. Circular DNA Encodes for several RNA’s and Proteins Mitochondria produces energy for the body. What Is Kearns-Sayre Syndrome. mitochondrial encephalomyopathies Sporadic Mutations Heteroplasmy occurs. Diagnosis.
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Kearns-Sayre Syndrome By Tommy Antony
Mitochondrial DNA • Circular DNA • Encodes for several RNA’s and Proteins • Mitochondria produces energy for the body
What Is Kearns-Sayre Syndrome • mitochondrial encephalomyopathies • Sporadic Mutations • Heteroplasmy occurs
Diagnosis • Eye muscle paralysis • Pigment Accumulation • Heart Disease • Testing
Symptoms • Usually occur before age 20 • Other symptoms include, skeletal muscle weakness, short stature, hearing loss and deafness, ataxia impaired cognitive function and diabetes. • Pearson Syndrome
Treatment • No cure • Cardiac treatments • Coenzyme Q10
Reference • "Kearns Sayre Syndrome." 17 Feb. 2004. 19 Mar. 2006 <http://www.medterms.com/script/main/art.asp?articlekey=30811>. • McKusick, Victor A., comp. 24 Sept. 1992. John Hopkins U. 19 Mar. 2006 </www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=530000>. • "Ninds Kearns-Sayre Syndrome Information Page." 24 Jan. 2006. National Institute of Neurological Disorders and Stroke. 19 Mar. 2006 <http://www.ninds.nih.gov/disorders/kearns_sayre/kearns_sayre.htm>. • Pasternak, Jack J. 2nd ed. Hoboken: John Wiley & Son, Inc, 2005. 358-359. • Posner, Ewa. "Kearns-Sayre Syndrome." (2005). 19 Mar. 2006 <http://www.emedicine.com/ped/topic2763.htm#section~author_information>.