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Bio 342 Human Physiology

This course explores the function of cells, tissues, organs, and organ systems in maintaining stability and the consequences of disruptions. Topics include homeostatic mechanisms, experimental basis of physiology, laboratory skills, critical thinking, and scientific communication.

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Bio 342 Human Physiology

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  1. Bio 342Human Physiology • Pick up a piece of paper from the piano. “Loose Canon” by LAGQ

  2. A physiologist asks… • How do things work in the human body? • How is stability achieved? • What are the causes and consequences of disruptions of stability? • Physicians ask “How can stability be restored?” • How do we know what’s going on inside the body?

  3. Theme of this course: Homeostasis

  4. First Demonstration for Bio 342 Human Physiology • Listen carefully to the music and to how it is interpreted • Observe the human body in action during the performance of the piece • Consider the activity of cells, tissues, and organs in the musicians “Loose Canon” by LAGQ

  5. Physiology in Action!Examples from the performance:

  6. BIO 342 HUMAN PHYSIOLOGY • PHYSIOLOGY: The study of the function of cells, tissues, organs, and organ systems. • THE TEXT: Widmaier et al. 20011 (12th ed.) • Chapter 2-5 review of other courses • Using your textbook

  7. General Course Objectives 1. To develop a basic understanding of the principles of physiology, with an emphasis on homeostatic mechanisms and negative feedback control. • 2. To develop an appreciation for the experimental basis of our knowledge of physiology. • 3. To sharpen laboratory skills with exercises that require forethought, planning, andrefinement.

  8. General Course Objectives • 4. To organize and analyze information so as to develop critical thinking skills. • 5. To write concisely in the form of scientific abstracts. • 6. To communicate effectively in oral form.

  9. The Syllabus (on the course websitehttp://webs.wofford.edu/davisgr/bio342/) • Office & home phone numbers • E-mail (davisgr@wofford.edu) • Lecture topics by week • Text chapters in parentheses • Read in advance of lectures

  10. A Website for this Course! • Check daily. • Get Study Questions and Powerpoint files via the website.

  11. LABORATORIES • 5-8 Computer setups, ~20 persons per lab • 2:00 - 5:00 Mon (Davis) • 8:00 -11:00 am Tuesday (Nguyen) • 2:30 – 5:30 Tue (Davis) • 2:00 – 5:00 Wednesday (Nguyen) • 2:30 – 5:30 Thursday (Davis) • May shift topics due to availability of animals • One Lab Report in the form of abstracts • very concise, based on lab data • Incorporate statistics • With revision and resubmission • No separate lab tests; lecture tests include labs • This week’s Lab: Using live animals!

  12. GRADING • 3 lecture tests = 60% • multiple choice (choose all correct answers) • Some short answer • Rarely fill in the blank • Sometime create or complete graph or diagram • discussion question(s) from a list • Cumulative final exam = 20% • Other work = 20% • Abstract = 10% • 1 Question Quizzes (1QQs) = 10%

  13. Honor Code • All worked is to be “pledged.” • Issues of plagiarism to be handled by the Honor Court

  14. ODDS AND ENDS • Limited use of electronics in classroom & lab • Only for class/lab-related activities • NO FOOD or DRINKS in Lab • Possible limited lab swapping • under special circumstance • students arrange paired swap • prior approval • See “Attendance” webpage • BE ON TIME, READY TO GET TO WORK • DON’T ASK ABOUT LENGTH OF LAB • BE READY TO START ON TIME

  15. Study Questions & Quizzes • Questions provided for each chapter (On the website!) • Read the book and answer the questions PRIOR to class meeting • Class time is used to deal with problematical topics and reinforce the major concepts • Be ready for 1QQs

  16. Study Questions & Quizzes • Rationale for this format: • See what Dr. Davis thinks you ought to emphasize • Writing helps to consolidate memory and recall • Greater effort results in better retention and understanding • Students are not passive learners • Able to cover more information • Improve MCAT, DCAT and GRE scores

  17. Group advising for premed students Monday, Sept 5. • For those interested in medical school, your premed advisor will present and answer questions at the following times in Olin theater: • Freshmen: 8-8:20 pm Advisor Dr. Moss, bring your course schedules. • Sophomores: 8:25-8:45 pm Advisor Dr. Moeller • Juniors: 8:50-9:10 pm Advisor Dr. Moeller • Seniors: 9:15-9:35 pm Advisor Dr. Moss • For those interested in Physician Assistant (PA) programs you can meet with your PA advisor Dr. Moss in Olin room 118 at 8:30-9 pm (all years) • For those students interested in graduate programs in biology and allied fields we will have an interest/advising meeting in the near future.

  18. More stuff • Arrive early for lecture and lab • Pay attention (no cell phones, email, Facebook, etc. during lecture or lab) • Take notes on what is said….don’t wait for boardwork.

  19. 1st Assignment:Personal Informationdue on Friday

  20. Chapter 1 and parts of 16 • Tissues • Organs • Organ Systems • Homeostasis • Negative & positive feedback, acclimation • Two detailed examples: Thermoregulation and Glucose Homeostasis

  21. Genetics & Development Cell & Molecular 200

  22. Cell types • Neuron • Hepatocyte • Cardiac myofiber • Septal cell (lung) • Purkinje fiber (heart) • Melanocyte • Enteroendocrine cell • Simple cuboidal cell of the proximal renal tubule • Basal cell of stratum germinativum (skin) • Endothelial cell • Fibroblast • Osteocyte • Chondrocyte • Acinar cell of pancreas • Beta cell of Islet of Langerhans • Schwann cell

  23. More cell types • Sertoli cell • Leydig cell • Hair cell (inner ear) • Smooth myofiber of arteriole • Mast cell • Unilocular adipocyte • Osteoblast • Monocyte • Langhan’s giant cell • Megakaryocyte • Satellite cell (ganglion) • Myofibroblast in capsule of spleen • Odontoblast • Ameloblast • Myoepithelial cell of salivary gland

  24. Even More Cell Types • Parietal cell • Chief cell (stomach) • Paneth cell • Podocyte • Juxtaglomerular cell • Cell of the macula densa • Chromaffin cell (adrenal medulla) • Cell of the corona radiata • Spermatogonia • Granulosa lutein cell • Secretory cell of the zona glomerulosa • Secretory cell of the zonal fasciculata

  25. Histology Name and organ and verify it has all 4 tissue types.

  26. Figure 01.01c Anatomy

  27. The Human Body:A Society of Cells • Imagine you are a cell. Ask yourself: • How did I get here?  • What do I do for myself? (What are my special characteristics and functions?)  • What do I do for the person in whom I reside? (What are my contributions to the whole organism? To homeostasis?)  • What do I need simply to survive? • What do the other cells provide for me that I cannot obtain alone? • What governs my actions?  • How long will I live? • Can I be replaced? If so, how? • What would happen to the organism if I along with all the other cells of my type were to fail to function properly?

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