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Background

Seasonal pattern of influenza activity in the Philippines ( 2006-2008): Research Implications to recommendations for influenza vaccination. Lucero MG, Inobaya A, Bautista A, Tan A, Arguelles V, Dureza C, Mercado E, Barrientos A, Tallo V and Olveda RM

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Background

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  1. Seasonal pattern of influenza activity in the Philippines (2006-2008): Research Implications to recommendations for influenza vaccination Lucero MG, Inobaya A, Bautista A, Tan A, Arguelles V, Dureza C, Mercado E, Barrientos A, Tallo V and Olveda RM Research Institute for Tropical Medicine National Influenza Center, Philippines

  2. Background • Influenza virus infection – extensive studies in temperate countries • Few studies in tropical countries like the Philippines • National Influenza surveillance established in 2005 after the creation of an NIC.

  3. Objective To present the results of the national influenza surveillance from 2006 to 2008 and determine if a seasonal pattern of influenza infection is observed in the Philippines.

  4. Methods • Study Design: Retrospective analysis • Database: ILI surveillance data from 2006-2008 • Sentinel sites: health centers and OPD clinics of hospitals in 11 regions in the Philippines 2008: Influenza Burden of Disease Study (BOD) Baguio City

  5. Surveillance Procedures

  6. Influenza virus identification • Virus isolation in cell culture for • Influenza virus and other respiratory viruses (starting 2006 to present) • Real-time PCR assay: H1, H3 and avian H5 subtypes – for 25% of swabs in BOD study in late 2008 and for suspected outbreaks during routine surveillance

  7. Results Influenza-Like Illness (ILI) Surveillance in the Philippines, 2005 - 2008

  8. Distribution of Influenza-positive ILI cases by morbidity week from 2006-2008 National Influenza Surveillance Network

  9. Influenza types identified in the Philippines from 2006 to 2008

  10. VACCINE COMPOSITION RECOMMENDATIONS FROM WHO and PHILIPPINE INFLUENZA STRAINS IDENTIFIED

  11. Summary of the results of the 3-year surveillance: 1. Influenza virus activity is found all throughout the year but activity is highest starting 3rd week of May and continues till the months of October or November with usually two peaks observed during this period. 2. Different dominant organisms are associated with each peak. 3. Not all vaccine composition recommendations matched influenza strains identified during the years studied. Dominant influenza strain for 2007 was not covered by the vaccine recommendations for that year. Dominant flu strain for 2008 was covered only by Southern Hemisphere vaccine recommendations.

  12. Implications of findings of 3-year surveillance: Influenza vaccination should be given before May of each year or before school opening in June. NIC should continue its activities of timely submission of data and isolates to WHO for better understanding of vaccine recommendations for the Philippines and other Asian countries. Northern or Southern Hemisphere vaccine recommendation to be followed? Limitation of study: Only mild ILI cases studied. No data on hospital SARI cases.

  13. Acknowledgment: Dr. Eric Tayag: National Epidemiology Center (NEC), Department of Health NEC Epidemiologists 3. Regional Health Officers, Provincial Health Officers, RESU, CESU, Chief of Participating Hospitals, Participating Health Center personnel of Regions I, II, III, V, VI, VII, IX, CAR, NCR, X, XI, XII, Participating Tertiary Hospitals in NCR and Baguio City 4. Influenza Surveillance Officers 5. RITM-NIC personnel

  14. Acknowledgment: Centers for Disease Control and Prevention (CDC), Atlanta, USA WHO

  15. CHEERS ! THANK YOU 7-10 June 2011 rolvedamd_ritm_doh@yahoo.com

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