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It Takes Teamwork

It Takes Teamwork. Sperm Anatomy. Acrosome enzymes: hyaluronidase , acrosin , neuraminidase. Fertilization and Implantation. Eggs are viable for 72 hours Sperm is viable for 48 hours. Implantation occurs about 5-6 days after conception. Development Week 1. Blastocyst Inner Cell Mass

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It Takes Teamwork

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  1. It Takes Teamwork

  2. Sperm Anatomy Acrosome enzymes: hyaluronidase, acrosin, neuraminidase

  3. Fertilization and Implantation Eggs are viable for 72 hours Sperm is viable for 48 hours Implantation occurs about 5-6 days after conception

  4. Development Week 1 Blastocyst Inner Cell Mass (Embryonic Stem Cells)

  5. Developmental Week 2 • Embryonic Germ Cell Layers: • Endoderm • Mesoderm • Ectoderm

  6. Neural Development (Weeks 3-4) • Neural Plate • Neural Groove • Neural Fold • Neural Crest • Neural Tube

  7. Neural Tube Defects Anencephaly: Failed closure of the Anterior Neuropore SpinaBifida: Failed closure of the Posterior Neuropore

  8. Steps in Neural Development • Mitosis • Migration • Differentiation • Dendritic Sprouting and Bulb Growth • Synaptogenesis • Cell Death • Dendritic Pruning • Myelination

  9. Mitosis

  10. Migration • Growth Cones form and use: • Radial Glia • Contact Inhibition • Contact Adhesion • Fasciculation • Guide Posts • Chemotropism

  11. Growth Cones Growth Cone

  12. Radial Glia • Act like scaffolding • to assist movement • of neurons during • development

  13. Contact Inhibition/Adhesion The growth cones of migrating cells can be attracted to other cell surfaces by contact adhesion molecules on those cells. Likewise, growth cones of migrating cells can be repelled from other cell surfaces by contact inhibition molecules on those cells.

  14. Fasciculation Adhesion molecules allow the bonding of same type axons to form a nerve bundle.

  15. Guide Posts Intermediate targets that help guide or direct the growth cone of the migrating cell in the proper direction

  16. Chemotropism Target Cell or Tissue Target tissues or cells can release chemicals that will attract the specific growth cones of migrating cells.

  17. Differentiation

  18. Dendritic Sprouting

  19. Synaptogenesis

  20. Cell Death and Dendritic Pruning

  21. Myelination Major growth occurs from birthto 2 years of age Cephalocaudal Development: from head to toe (tail) Proximodistal Development: from midline to the periphery Readiness Principle: Until children reach a state of readiness, they will be unable to perform a task, even with training and practice.

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