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Gottesman 1991

Gottesman 1991. By Pooja, Jessica and Shohum. Aims. To investigate the risk of developing schizophrenia in different types of genetic relatives of a schizophrenic. Procedures. C ompiled data from 40 family studies from the best Western European studies reported over the past century.

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Gottesman 1991

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  1. Gottesman 1991 By Pooja, Jessica and Shohum

  2. Aims • To investigate the risk of developing schizophrenia in different types of genetic relatives of a schizophrenic.

  3. Procedures • Compiled data from 40 family studies from the best Western European studies reported over the past century.

  4. Findings

  5. Conclusions • Risk for cousins (2%) is only slightly greater than the general population risk. • Second-degree relatives have a risk of around 5%, while first-degree relatives have a risk close to 10%. • With one schizophrenic parent the risk was 6% with two it rose to 46%. • Monozygotic twins had a 48% concordance rate. • Dizygotic twins had a 17%. • Concordance rates in this study are not 100% which can suggest that the cause of schizophrenia may not be entirely genetic and other factors such as the environment and cognition may also play a role in the risk of an individual developing schizophrenia.

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