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From Science Daily: • Taking small tissue samples from patients with lung cancer and examining them under a microscope (a procedure that falls into the field ofhistology) is now being utilized to better tailor the chemotherapy treatments to improve survival in some patients with non-small cell lung cancer, according to a study presented at the 2008 Chicago Multidisciplinary Symposium in Thoracic Oncology, cosponsored by ASTRO, ASCO, IASLC and the University of Chicago.
What is histology? • The study of the microscopic structure of tissue
4 types of tissues found in the human body • Epithelial tissue • Muscle tissue • Nervous tissue • Connective tissue
Characteristics of Epithelial tissue • Always has a free surface • Uninterrupted layer of cells • Minimal intracellular space • Always attached to a basement membrane • Does NOT contain blood vessels (avascular) • Many types have have cilia or micro- villi on surface
Functions of Epithelial Tissue • Provides physical protection • Maintains Homeostasis • Sensory organ • Touch receptors • Temperature receptors • Pain receptors • Pressure receptors • Produces specialized secretions
Epithelial tissue is classified by number of layers and by shape of the exposed cells
Cell layers • Simple-one layer of cells over basement
Cell layers • Stratified-several layer of cells over basement
Cell shape • Squamous-flat, scale-like cells
Cell Shape • Cuboidal- square-like cells
Cell Shape • Columnar- long, rod-like cells
To describe the tissue: the word describing cell layer comes before word describing cell shapeExample: simple squamous
Pseudostratified • Single layer of cells, but placement of nuclei in cells makes it appear to be multiple layers
Transitional Epithelium • Consists of multiple layers of cells that can contract and expand
Glandular Epithelial Tissue • Produces secretions Goblet Cells-produce mucin which combines with water to from mucus
All the epi- words • Epithlium=layer of cells • Epidermis=skin • Endodermis=layer of organs