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A). Healthy. 100. 90. 80. LAB1. 70. LAB2. % methylation. 60. LAB3. 50. LAB4. 40. LAB5. 30. 20. 10. 0. NESP55 GNAS-AS XL α s A/B. Complete GOM/LOM. B). 100. 90. 80. LAB1. 70. LAB2. 60. LAB3. % methylation. 50. LAB4. 40. LAB5. 30. 20.

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  1. A) Healthy 100 90 80 LAB1 70 LAB2 % methylation 60 LAB3 50 LAB4 40 LAB5 30 20 10 0 NESP55 GNAS-AS XLαs A/B

  2. Complete GOM/LOM B) 100 90 80 LAB1 70 LAB2 60 LAB3 % methylation 50 LAB4 40 LAB5 30 20 10 0 NESP55 GNAS-AS XLαs A/B

  3. C) Isolated LOM at AB 100 90 80 LAB1 70 LAB2 60 % methylation LAB3 50 LAB4 40 LAB5 30 20 10 0 NESP55 GNAS-AS XLαs A/B

  4. D) Partial GOM/LOM 100 90 80 LAB1 70 LAB2 60 % methylation LAB3 50 LAB4 40 LAB5 30 20 10 0 NESP55 GNAS-AS XLαs A/B

  5. E) Partial GOM/LOM 100 90 80 LAB1 70 LAB2 60 LAB3 % methylation 50 LAB4 40 LAB5 30 20 10 0 NESP55 GNAS-AS XLαs A/B

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