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West-Life

Join Chris Morris from STFC, UK to explore the evolving landscape of structural biology. Discover how researchers overcome obstacles with small samples and noisy data to deliver results. Learn how West-Life facilitates access to experimental facilities and streamlines workflows for improved research outcomes.

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West-Life

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  1. Chris Morris, STFC, UK chris.morris@stfc.ac.uk West-Life

  2. New challenges for structural biology • Combined techniques • not always acting as an expert • Small samples • Data noisy and incomplete • Deliver results to other life scientists • 73% working on eukaryotic rather than prokaryotic systems • 84% working on complexes rather than single gene products • Each research team routinely uses three-four different techniques • 83% would use combined SB techniques more often if it was easier to get access to experimental facilities • 73% of the cases found it hard to combine software tools for different techniques in integrated workflows

  3. Why EUDAT? • Raw experimental data -> reduced data -> structure • Large experimental facilities have own resource • small ones need help • Extensible • Reinvent nothing • Virtual folder view of research project

  4. The expected future impact • Automatically record provenance metadata when data used • Challenge to develop new algorithms for combined techniques • Data volume: • Combined output of European SB facilities > LHC • XFEL will double it

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