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West-Life

Chris Morris, STFC, UK chris.morris@stfc.ac.uk. West-Life. New challenges for structural biology. Combined techniques not always acting as an expert Small samples Data noisy and incomplete Deliver results to other life scientists.

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West-Life

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  1. Chris Morris, STFC, UK chris.morris@stfc.ac.uk West-Life

  2. New challenges for structural biology • Combined techniques • not always acting as an expert • Small samples • Data noisy and incomplete • Deliver results to other life scientists • 73% working on eukaryotic rather than prokaryotic systems • 84% working on complexes rather than single gene products • Each research team routinely uses three-four different techniques • 83% would use combined SB techniques more often if it was easier to get access to experimental facilities • 73% of the cases found it hard to combine software tools for different techniques in integrated workflows

  3. Why EUDAT? • Raw experimental data -> reduced data -> structure • Large experimental facilities have own resource • small ones need help • Extensible • Reinvent nothing • Virtual folder view of research project

  4. The expected future impact • Automatically record provenance metadata when data used • Challenge to develop new algorithms for combined techniques • Data volume: • Combined output of European SB facilities > LHC • XFEL will double it

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