1 / 15

University of Pittsburgh Senior Design – BioE1160

University of Pittsburgh Senior Design – BioE1160. Design of a Malignant Hyperthermia Susceptibility Screening Device Sara Doll Lisa Kaczmarski Philip Magcalas Department of Anesthesiology Children’s Hospital of Pittsburgh. Overview.

wyatt-castro
Download Presentation

University of Pittsburgh Senior Design – BioE1160

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript

  1. University of Pittsburgh Senior Design – BioE1160 Design of a Malignant Hyperthermia Susceptibility Screening DeviceSara DollLisa KaczmarskiPhilip MagcalasDepartment of AnesthesiologyChildren’s Hospital of Pittsburgh

  2. Overview Malignant Hyperthermia (MH) is a chain reaction event wherein susceptible patients, when administered common gas anesthetics, undergo drastic temperature elevation. There are currently no standard devices or procedures in common practice to screen the general population for this condition. The solution lies in the design of a device that measures the isometric force produced by the thumb when the ulnar nerve is stimulated. Such a device would be beneficial to: • Anesthesiologists • Patients • And their families

  3. Project Goals • Establish a clear fundamental understanding of the effects of MH on muscle fatigue • Create a device design which comfortably accommodates the patient, while allowing for measurement of a solely isometric contraction force • Create a device design which would allow accurate measurements and clear methods of interpretation • Test and assess the effectiveness of the device in measuring forces within a specific range • Complete all of the above on a limited budget

  4. Device Features & Benefits Arm restraint platform Firmly restrain patient’s forearm, hand, and thumb in a comfortable manner for all morphological body types Force sensor Accurately and safely measure contraction force of thumb Overall Maintain simplicity for ease of assembly, use, and data interpretation Support Adjustable mounting assembly that can be tightly secured during testing

  5. Proposed Design

  6. Other possible solutions… Arm restraint platform • Adjustable straps • Adjustable restraint ‘walls’ • Interchangeable polymer thumb ‘molds’ • Fixed metal ring with velcro strap • Cushioned plastic • Laminated wood Force sensor • Strain gage • Force transducer connected to metal ring Support • Vises • Bed-mount

  7. Competitors

  8. Collaborations Universitat Wurzburg, Germany • Andreas Hoyer, M.D. • Melanie Veeser, M.D. Children’s Hospital of Pittsburgh • Dr. Robert Sclabassi, M.D., Ph.D. Neurologist, Professor in Departments of Neurological Surgery, Psychiatry, Neuroscience, Electrical Engineering, Mechanical Engineering and Bioengineering • Dr. Barbara Brandom, M.D. Anesthesiologist, Director of North American MH Registry, Professor of Anesthesiology

  9. Technology SolidWorks - Mechanical component design National Instruments’ LabView - Circuitry design Swanson Center for Product Innovation - Prototypes, Final Product

  10. People Robert J. Sclabassi, M.D., Ph.D. Barbara Brandom, M.D. Andreas Hoyer, M.D. Mingui Sun, Ph.D. & George Stetten, M.D., Ph.D. Software Labview - B69 SolidWorks - B62 Locations Benedum Design Lab - B62 BioE Instrumentation Lab - B69 Children's Hospital of Pittsburgh Manufacturing Swanson Center for Product Innovation Pitt Machining Shop Product Assistance Component part companies SolidWorks instructors But most importantly! Time Money Assumptions About Resources

  11. Schedule December - Preliminary SolidWorks drawing for arm board, support - Preliminary circuitry design - Order force transducer (Grass – model FT03) January - Gather materials for prototype - Build initial prototype February - Prototype testing - Design revisions - Finalize SolidWorks drawing - Order final materials March - Build/Assemble device April - Device testing, as time allows - Draft final report and presentation

  12. Who will be accountable for what

  13. Current Status • General MH research • Initial project meetings with mentor • Project planning/development • Objective Tree • Function-Means Analysis • Human Factors testing plan • Goals, schedule, and milestones defined (Gantt chart) • Device specifications defined • Preliminary Design Schematic • Observation of Dr. Hoyer’s device in use

  14. Acknowledgements • Robert J. Sclabassi, M.D., Ph.D. • Barbara Brandom, M.D. • Andreas Hoyer, M.D.

  15. …Any Questions? • This is MH: =-( • This is MH with our device: =)

More Related