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Applied WALKER-TESSNER MODEL FOR Major Depressive Disorder. Neuromaturational Factors (Biological) Neurotransmitters Hormones Studies: Janowsky et. Al (1972), Delgado and Moreno (2000) on i mbalances in neurotransmitters affecting depression. More Evidence:
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Applied WALKER-TESSNER MODEL FOR Major Depressive Disorder Neuromaturational Factors (Biological) Neurotransmitters Hormones Studies: Janowsky et. Al (1972), Delgado and Moreno (2000) on imbalances in neurotransmitters affecting depression. More Evidence: Imbalances in hormone levels (cortisol and depression). Read about Cushing’s syndrome in depression. Stress (Sociocultural Factors): 1) Severe life events and social status. Studies: Brown and Harris (1978) on social vulnerability of women in depression as well as the social vulnerability model. Constitutional (biological) vulnerability PSYCHIATRIC OUTCOME (Depression) • Cognitive Factors: • 1. Irrational and Illogical thinking • 2. Cognitive distortions • 3. Negative thinking patterns • Studies: • 1) Ellis (1962) on faulty conclusions/irrational believes leading to self-defeating conclusions (depression). • 2) Beck (1976) argues that when people have negative cognitive schemas they can interfere with information processing and lead to depressive feelings • 3) Alloy et. Al (1999) studied relationship between negative thinking and development of depression. Inherited Factors (Biological): 1) Genetic Predisposition (expression for Depression) Studies: Nurnberger and Gershon (1982) on concordance rates in twin studies for depression.