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Day1 Plenary Session

Day1 Plenary Session. Lecture 1 : Propagation of the neurodegenerative process in PD and the Prion-like hypothesis. Lecture 2 : Can the interaction between genetics, environment, and behavior be a key determinant of PD expression.

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Day1 Plenary Session

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  1. Day1Plenary Session Lecture 1: Propagation of the neurodegenerative process in PD and the Prion-like hypothesis Lecture 2: Can the interaction between genetics, environment, and behavior be a key determinant of PD expression Lecture 3: What epidemiological and preclinical studies teach us about inflammation and PD Lecture 4: Developing new treatments founded on the basic science of PD Special Lecture 1:The Life and Times of James Parkinson Special Lecture 2:The Glory of Canadian Sciences and Parkinson's Disease

  2. Day 2Plenary Session Lecture 1: The spectrum of non-motor symptoms in PD Lecture 2: Dementia and psychiatric manifestations in PD Lecture 3: Contribution of functional neuroimaging to the understanding of non-motor manifestations of PD Lecture 4: The impact of other medical conditions on the course of PD WPC James Parkinson Lecture: Past, Present and Future of Parkinson’s Disease

  3. Day 3Plenary Session Lecture 1: Cell and gene-based technologies for restorative and neuroprotective therapies Lecture 2: Exercise, diet, and other lifestyle activities as treatments for Parkinson disease Lecture 3:Empowered patients and how they can help improve healthcare Lecture 4:Roles for healthcare professionals: multidisciplinary care for Parkinson disease. Special Lecture:Living Positively After a Diagnosis of Parkinson's

  4. Day 1 Parallel Session I Parallel Session: New genes and risk factors of PD Lecture 1: New PD genes and rare variants Lecture 2: Risk factors for sporadic PD Lecture 3: Genetics and gene environment interactions Parallel Session: Protein misfolding as a key pathogenic event Lecture 1: Alpha-synuclein conformation and neurodegeneration Lecture 2:Protein misfolding in neurodegenerative diseases Lecture 3: Link between lysosomal function and neurodegeneration in PD Parallel Session: Role of functional imaging modalities in the diagnosis and managementof PD Lecture 1: Structural imaging for PD: MRI and transcranial sonography (TCS) Lecture 2: Neurochemical imaging Lecture 3: Functional connectivity Parallel Session: Non-dopaminergic systems in PD: Anatomy, Biochemistry, and Pathology Lecture 1: Role of noradrenaline and serotonin systems for the development of non-motor symptoms Lecture 2: Impact of cholinergic dysfunction on the development of non-motor symptoms Lecture 3: Role of non-dopaminergic systems in the development of L-DOPA-induced dyskinesias

  5. Day 1 Parallel Session I Workshop 1:Why supporting research is crucial: from government to private funding agencies Workshop 2: Mitochondrial defect in PD: myth or reality? Workshop 3: Sexual issues in Parkinson's disease: assessment and intervention Workshop 4:Quality of life and comfort in the late stages of Parkinson's disease

  6. Day 1 Parallel Session II Parallel Session: Quality of life in Parkinson’s disease: several important determinants Lecture 1: Practical solutions to driving, early job loss, and relationship issues Lecture 2: Psychological solutions to dealing with pity, dignity, sense of worth and communication Lecture 3:Physical solutions to coping with pain, motor/non-motor, cognition, mood, and behavior Parallel Session: How Parkinson’s affects attention and memory Lecture 1: Memory and attention issues in Parkinson’s disease—clinical characteristics and mechanisms Lecture 2: Clinical Assessment of Cognition in PD Lecture 3: Practical management of cognitive deficits in Parkinson's disease; what can occupational therapists offer? Parallel Session: Experimental models of non-motor manifestations of PD Lecture 1: Animal models of hyper dopaminergic behavior in Parkinson’s disease Lecture 2: Animal models of sleep disorders in Parkinson’s disease Lecture 3: Animal models of gastrointestinal dysfunction in Parkinson’s disease Parallel Session: Optogenetic tools to study PD pathophysiology Lecture 1: Optical Neural Engineering Lecture 2: Regulation of Parkinsonian motor behaviors by optogenetic control of basal ganglia circuitry Lecture 3: Optical Interrogation of the dopaminergic systems

  7. Day 1 Parallel Session II Workshop 1: Everything you always wanted to know about genetics and that you never dared to ask Workshop 2: Howresearchers and people with Parkinson’s can advance clinical trials together Workshop 3: How drugs make it to your cabinet Workshop 4: Music, art, creativity and Parkinson's

  8. Day 2 Parallel Session I Parallel Session: PD or not PD - that is the question: Is it time to redefine/reclassify Parkinson’s disease? Lecture 1: Current definitions and diagnostic criteria: reasons for redefining the disorder. Lecture 2: The challenge of "prodromal" Parkinson's disease Lecture 3: Redefining Parkinson's disease: possible approaches to developing new diagnostic criteria Parallel Session: Hallucinations and related phenomena in PD Lecture 1: Prototypical and less common hallucinations Lecture 2: Where is the nucleus hallucinatorius and how it gets stimulated? Lecture 3: Management of hallucinations and related symptoms Parallel Session: Mitochondrial quality control mechanisms Lecture 1: Mitochondrial quality control- a matter of life and death for neurons Lecture 2: Mechanisms of mitophagy in Parkinson’s disease Lecture 3: Mitochondrial remodeling in the control of apoptosis Parallel Session: Ways for people with Parkinson’s to become empowered Lecture 1: Why and how people with Parkinson’s need empowerment - Finding your own niche Lecture 2: Evidence-based self-management practices Lecture 3: Increasing Parkinson’s advocacy effectiveness with lessons learned from other diseases

  9. Day 2 Parallel Session I Workshop 1: Benefits and risks of genetic testing Workshop 2: Sleep and fatigue in PD Workshop 3:Ethical dilemmas posed by new diagnostic and therapeutic technologies Workshop 4:Tricks of the trade: clever strategies to improve mobility

  10. Day 2 Parallel Session II Parallel Session: PD or look-alikes: how to diagnose them and what are their long-term prognoses? Lecture 1: Drug Induced Parkinsonism Lecture 2: PD or progressive supranuclear palsy Lecture 3: PD or Multiple system atrophy Parallel Session: Clinical trial outcomes—What do they really mean? Lecture 1: Clinical trial endpoints in PD – What is really meaningful? Lecture 2: The placebo effect: how it complicates clinical trial results Lecture 3: Slowing clinical progression in PD –can it be proven in clinical trials? Parallel Session: The search for new delivery methods for drugs Lecture 1: Improving oral drug delivery in PD – recent advances Lecture 2: Infusion therapies and other non-oral routes of drug delivery Lecture 3: Delivering therapeutic genes into the brain – a future way of drug delivery? Parallel Session: Is PD an axonopathy? Lecture 1: Pathological evidence for axonopathy in Parkinson’s disease Lecture 2: Evidence for synaptic dysfunction in Parkinson’s disease Lecture 3: Alterations in axonal transport in Parkinson’s disease

  11. Day 2 Parallel Session II Workshop:Choosing a care facility: When is it time? What are the options? Workshop: Do experimental models of Parkinson’s disease predict treatment outcome? Workshop: Complementary and integrative medicine Workshop: Dance and Parkinson’s: Why and How?

  12. Day 3 Parallel Session I Parallel Session: Update on Gaucher and Parkinson's diseases Lecture 1: What is new about the link between Gaucher mutations and Parkinsonism Lecture 2: Exploring mechanisms that underlie between mutations in Gaucher disease gene and synucleinopathy risk Lecture 3: How the understanding of Gaucher could lead to new therapies for Parkinson's Parallel Session: Newinsights into Parkinson's disease from experimental cell- and gene-based strategies Lecture 1: Use of human ES and iPS cells for cell replacement in Parkinson´s disease Lecture 2: Role of Sonic hedgehog in maintaining striatal homeostasis Lecture 3: Nurr1 as a therapeutic target for neuroprotection and disease modification in PD Parallel Session: Neurobiology and treatment of dyskinesias Lecture 1: Maladaptive plasticity in L-DOPA-induced dyskinesia: emerging role of serotonin transmission and other presynaptic factors Lecture 2: Pre- and post-synaptic molecular mechanism underlying L-DOPA-induced dyskinesia possible new pharmacological targets Lecture 3: Multiple dopamine-dependent synaptic mechanisms underlying dyskinesia in animal models Parallel Session: Pathophysiology and management of head drop and bent spine in PD: Are they dystonia or myopathy or both? Lecture 1: Myopathy causing camptocormia in idiopathic Parkinson's disease Lecture 2: Camptocormia: pathogenesis, classification, and response to therapy Lecture 3: Dropped head syndrome in Parkinson's disease

  13. Day 3 Parallel Session I Workshop 1: Whatyou need to know about DBS: Selection, side effects, and new device development Workshop 2:Is PD an accelerated form of aging? Workshop 3: Pain in PD Workshop 4: Speech and Parkinson’s

  14. Day 3 Parallel Session II Parallel Session: Freezing and falls Lecture 1: Freezing- Underlying mechanisms and the role of cueing Lecture 2: Why do persons with PD fall? Does treatment help to reduce falling? Lecture 3: The benefits of exercise in reducing falling in PD Parallel Session: Promising approaches to identify and validate biomarkers Lecture 1: What are biomarkers and why do we need them? Lecture 2: Update on unbiased methodologies to identify biomarkers Lecture 3: Emerging biomarkers Parallel Session: Drug development challenges: from the pharmaceutical industry, regulatory agencies, and patient protection organizations perspective Lecture 1: Drug development challenges-Pharmaceutical industry perspective Lecture 2: Drug development challenges - A regulatory perspective Lecture 3: Drug development challenges-Patient protection agency perspective Parallel Session: How should levodopa induced dyskinesia be managed today? Lecture 1: Recognizing the subtypes and assessing severity of dyskinesia and the clinical impact Lecture 2: Current management of LID – medical and surgical Lecture 3:Future Management of LID: What’s in the pipeline?

  15. Day 3 Parallel Session II Workshop 1: The role of people with Parkinson's in the research process: How are they prepared and what can they do? Workshop 2: Which physical and mental exercises are good for people with Parkinson’s? Workshop 3: Parkinson's and Mood Changes: Depression, Apathy and Anxiety

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