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Non-Pneumatic Anti-Shock Garment (NASG) POPPHI 2009 Update Suellen Miller, CNM, PhD Director, Safe Motherhood Programs, Bixby Center for Global Reproductive Health, UCSF. Presented by Carinne Meyer, MA, MPH. The NASG: Low-cost, Low Tech Life Saving Device. Update on Research.
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Non-Pneumatic Anti-Shock Garment (NASG)POPPHI 2009 Update Suellen Miller, CNM, PhDDirector, Safe Motherhood Programs, Bixby Center for Global Reproductive Health, UCSF Presented by Carinne Meyer, MA, MPH
Update on Research • Nigeria: Pre-Post Study (Completed) • Egypt:Pre-Post Study (Completed) • Zambia/Zimbabwe: Cluster Randomized Trial (In Progress)
Nigeria Study (Mar. 04 – Nov. 08) • Pre-intervention/intervention study design • 12 referral hospitals in Northern and Southern Nigeria • Entry criteria were OH of any etiology (> = 750 ml) and one clinical sign of shock. • Outcomes: mean measured blood loss and mortality.
Egypt Study (June 06 – May 08) • Pre-intervention/intervention study design • 2 referral facilities in Egypt • Entry criteria were OH of any etiology (> = 750 ml) and one clinical sign of shock. • Outcomes: mean measured blood loss, mortality, severe morbidities and extreme adverse outcomes.
Zambia/Zimbabwe RCT Design: Cluster Randomized Trial Funding: NIH and Gates Foundation Data Coordination: WHO, RHRU Data Management: Centro Rosario Estudios Perinatales (CREP) (Argentina) OpenClinica Research Collaboration: University Teaching Hospital in Lusaka, Zambia and the University of Zimbabwe (UZ-UCSF RH Collaborative)
Why a RCT? The RCT is designed to determine if early application at the primary care level by midwives will IMPROVE MATERNAL OUTCOMES.
Randomized Cluster Trial Clinics Referral Hospital
Study Timeline LUSAKA – Phase 1 LUSAKA – Phase 2 LUSAKA – Phase 3 May 2009 October 2009 October 2007 October 2008 June 2008 July 2009 Feb 2009 HARARE – Phase 1 HARARE – Phase 2 HARARE – Phase 3 COPPERBELT– Phase 1 COPPERBELT– Phase 2 COPPERBELT– Phase 3