1 / 75

Laboratory Automation Integrating equipment into a multi-vendor world

Laboratory Automation Integrating equipment into a multi-vendor world . INTRODUCTION. INTEGRATION. SCHEDULING. SMALL SYSTEMS. HIGH THROUGHPUT SYSTEMS. DATA HANDLING. SUMMARY. Programme. Laboratory Automation Integrating equipment into a multi-vendor world Introduction. Malcolm Crook

yule
Download Presentation

Laboratory Automation Integrating equipment into a multi-vendor world

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript

  1. Laboratory Automation Integrating equipmentinto a multi-vendor world

  2. INTRODUCTION INTEGRATION SCHEDULING SMALL SYSTEMS HIGH THROUGHPUT SYSTEMS DATA HANDLING SUMMARY Programme

  3. Laboratory Automation Integrating equipmentinto a multi-vendor world Introduction

  4. Malcolm Crook Synthetic chemist 12 years in industry (BP) 19 years in automation 11 years running PAA 25 years writing software Visiting Reader in Chemistry at University of Surrey Your Presenter

  5. Laboratory Automation Integrating equipmentinto a multi-vendor world Integration

  6. What do PAA offer • Scheduling software • OVERLORD™ Workstation • OVERLORD™ Scheduler • Systems integration expertise • Data handling expertise • links to LIMS • links to databases • wide range of peripherals

  7. Plate readers Pipettingrobots PerkinElmer products

  8. Robots

  9. Dextrous gripper Long reach Dynamic vertical reach Mitsubishi

  10. Laboratory Automation Integrating equipmentinto a multi-vendor world Scheduling

  11. Scheduling Two types: • Real time scheduling • All decisions are taken during the time frame of the run • i.e. once the “GO” button is pressed • Pre-emptive scheduling • All decisions are taken before the run starts • i.e. before the “GO” button is pressed

  12. Real time scheduling • Advantages: • flexible • decisions can be taken during the run • error recovery easy • Disadvantages • accurate timings are more difficult to set up • two accurate timings in a run are impossible

  13. Pre-emptive scheduling • Advantages: • one or more accurate timings are guaranteed • easy to set up • Disadvantages • inflexible • decisions can not be taken during the run • error recovery more difficult

  14. Scheduling - the choice real-time pre-emptive either

  15. Laboratory Automation Integrating equipmentinto a multi-vendor world

  16. Our Automated Systems • complete solution using existing equipment • complete integration with other equipment • complete integration of hardware / software • integrated data handling

  17. FEATURES • PC based, Windows 2000/XP • full password and user identification • full interfacing with LIMS via text files • icon based, flow chart interface • on-line context sensitive manual • drag and drop setup • European language support

  18. OVERLORD™ • flow diagrams • hierarchical control • interface • instrument control • general functionality • connection to the outside world • 21CFR user access • expandability

  19. flow diagrams • Natural method of experiment description • easy to understand • easy to explain to another • easy to check logic

  20. comment N = 3 loops N = 3 Loop for n samples Action 1 Action 2 N = N + 1 Next sample All done

  21. comment Loop for n samples Action 1 Action 2 Next sample All done

  22. hierarchical control • Organised programming • logical units of operations • reusable procedures

  23. Main control loop procedural unit 2 procedural unit 3 procedural unit 1 sub unit 1 sub unit 2 sub unit 3 etc .... OVERLORD™

  24. Run sample preparation loop procedural unit 2 procedural unit 3 dilute sample Pick sample plate from hotel Place on Hamilton Pick blank plate from hotel etc .... OVERLORD™

  25. interface • flow diagram analogue • automatically filled in to aid programming • interface follows Microsoft visual specifications

  26. Information header about procedure Body of actions in procedure End of procedure Values & description at runtime Scroll around the procedure

  27. Palette of available commands Toolbar of common functions

  28. Information header about procedure Branching on condition Robot action tooltips to aid interpretation

  29. List of procedures for overview of complete method

  30. Instrument control • any device that can be controlled by • serial communications • switch on/off • variable voltage • use of equipment native control software • with automation interface • without automation interface

  31. Runtime • full self documentation/audit trail • data storage on server/local disc • clear, easy to read runtime interface

  32. Laboratory Automation Integrating equipmentinto a multi-vendor world Example of real time scheduling 1

  33. Plate reading • Process a stack of plates • pass through a plate reader • collate the results

  34. Matrix PlateMate Plus Hudson Plate Crane Bulk dispenser Plate washer Plate reader

  35. Laboratory Automation Integrating equipmentinto a multi-vendor world Example of real time scheduling 2

  36. MultiPROBE SWAP robot

  37. PlateSTAK

  38. PlateSTAK

  39. Laboratory Automation Integrating equipmentinto a multi-vendor world Example of pre-emptive scheduling

  40. Toolbar of common functions Start with new assay for schedule Information header about procedure

  41. Start with plate types in assay

  42. Fill in the assay name Drag and drop the actions in the assay

  43. Fill in the actions

  44. optimise

More Related