1 / 11

Antiretroviral therapy

Antiretroviral therapy. ARVs cannot cure the HIV virus ARVs prevent the virus from multiplying: - reduce the levels of virus in the blood - immune system has opportunity to recover People on ARVs can remain well for many years . Antiretroviral therapy.

yvon
Download Presentation

Antiretroviral therapy

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript

  1. Antiretroviral therapy • ARVs cannot cure the HIV virus • ARVs prevent the virus from multiplying: - reduce the levels of virus in the blood - immune system has opportunity to recover • People on ARVs can remain well for many years

  2. Antiretroviral therapy • Three classes of antiretroviral drugs: • nucleotide reverse transcriptase inhibitors (NRTIs) • non-nucleotide reverse transcriptase inhibitors (NNRTIs) • Protease inhibitors (PIs) • Life-long triple therapy • HAART: “highly active antiretroviral therapy” • Antiretrovirals are on WHO essential drugs list

  3. Continued impact of HAART on AIDS deaths in some Western European countries, 1998-2002 1400 Italy 1200 Spain Germany 1000 United Kingdom 800 Number of AIDS deaths 600 400 200 0 1998 1999 2000 2001 2002 Year Source: HIV/AIDS surveillance in Europe (2002). End-of-year report. Data compiled by the European Centre for the Epidemiological Monitoring of AIDS

  4. Antiretrovirals - challenges • High costs • Must be taken for life • Must be taken correctly 95% of the time • Potential for side effects • Regular laboratory monitoring required • Resistance

  5. Resistance • Drug resistance = organism is no longer sensitive to the drug • Antiretrovirals, Anti TB drugs, STI drugs • Influenced by: • characteristics of the organism • inadequate dose • incorrect dosage interval • inadequate treatment period • Using combinations of drugs reduces potential for resistance

  6. HIV and TB treatment programs Before starting HIV or TB treatment programs, think about: What factors influence whether people will: • take the right dose at the right time • take the drug for the required period of time (ARVs for life)

More Related