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BONE PAIN PALLIATION : SUPPORTING ROLE OF STAFF DURING THE RADIONUCLIDE TREATMENT. East Tallinn Central Hospital, Department of Nuclear Medicine, Tallinn, Estonia. GALINA S H AMARINA EVE P ALOTU. The World – small or big?. PAIN.
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BONE PAIN PALLIATION:SUPPORTING ROLE OF STAFF DURING THE RADIONUCLIDE TREATMENT East Tallinn Central Hospital, Department of Nuclear Medicine, Tallinn, Estonia GALINA SHAMARINA EVE PALOTU
PAIN • Pain is one of the main factors which is affecting the quality of life • Pain has a complex nature and different factors contribute to the patient’s perception of pain
Symptoms of debility Noncancer pathology Side-effects of therapy Cancer SOMATIC SOURCE Loss of social position Bureaucraticbungling Loss of income Friends who are don’t visit Loss of role of family DEPRESSIONANGERDelays in diagnosis Insomnia Unavailable doctors Sense of helplessness Irritability Disfigurement TOTAL PAINTherapeutic failure ANXIETY Fear of hospital or nursing home Fear of pain Worry about family Family finances Fare of death Loss of dignity and bodily control Spiritual unrestUncertainty about future Reproduced from A.J.McEwan “ Palliation of bone pain”
BONE METASTASES AFFECT QUALITY OF LIFE Pain Pathologic fractures - immobility Hypercalciemia Neurological problems Anxiety Depression
BONE SCINTIGRAPHY Multiple bone metastases Normal scan
RELIEF OF PAIN - GOAL IN TREATMENT OF BONE METASTASES relieving pain improve patient mobility improve patient function improve quality of life
QUALITY OF LIFE - HEALTH-RELATEDQUALITY CRITICAL PARAMETERS: 1. Physical functioning 2. Disease-and treatment-related symptoms 3. Psychological/emotionalsymptoms 4. Social interactions The "Palliative Care Quality of Life Instrument (PQLI)" in terminal cancer patients. Kyriaki Mystakidou, Eleni Tsilika, Vassilios Kouloulias. Health and Quality of Life Outcomes. http://www.hqlo.com/content/2/1/8
THE AIM OF THE STUDY Describe and analyse the aspects of the activities • nuclear medicine staff taking care of patients during the pain palliation with radioisotopes • patients participate in their treatment to get a sense of control over their disease
METHODS FOR EVALUATION OF QUALITY OF LIFE Specifically for cancer patients are suitable: • Karnofski ja WHO daily diaries questionary • Pain descriptor scale PDC • Patient’s analgetic use (opioid) • Personal’s global assessment PGA • Othes aspects of quality of life (patient’s daytime discomfort , quality of sleep etc)
DIARY OF PAIN ASSESSMENT Patient assesses daily his/her intensity of pain and completes the diary in 10 point scale - APS According to the APS the efficiency of treatment is evaluated and also to compare the different methods of therapy
ASSESSMENT OF PAIN RELIEF USING ANALOGUE PAIN SCALE Pain reliefChanges in APS Complete 80% and more Substantial 30-79% Minimal 10-29% No response 9% and less No Max pain 0 1 2 3 4 5 6 7 8 9 10 pain
PERSONAL’S GLOBAL ASSESSMENT 1. Condition is worse, patient feels more pain 2. Condition has not changed 3. Condition slightly better, slight relief of pain 4. Condition is moderatly better, moderate relief of pain and discomfort 5. Condition is much better, marked relief of pain and less discomfort 6. Condition is good, complete relief of pain and no discomfort during the daily performances
ANALGETIC USE • Prior the start of treatment all the doses of medications are recorded (24h) • All the doses are converted to morphine equivalents • During the treatment patient records all the doses of medications • Change in opiod analgetic use gives information of the treatment efficacy
CHARACTERISATION OF PATIENT POPULATION1995-2004 with bone pain due tometastatic breast (MBC) or prostate cancer (MPC) Median Age (y) NSAID Narcotics Total MPC 66 (40-79) 39 (73%) 13 (27%) 52 MBC 53 (36-68) 22 (75%) 8 ( 25%) 30 Total 61 (74%) 21 (26%) 82 23 59 Single BM Multiple BM
BONE PAIN RESPONSE TO THERAPY Complete 15 (18%) Substantial 43 (53%) Minimal 10 (12%) No 14 (17%) 82patients • Time of response 1 - 2 weeks after treatment • Duration of response - 4 - 24 weeks
BONE PAIN RESPONSE TO THERAPY Multiple Mts Single Mts Complete 15 3 12 Substantial 43 32 11 Minimal 10 10 0 No 14 14 0 82 59 23
CONCLUSIONS • Treatment with radioisotopes is an effective method for the palliation of metastatic pain providing relief in majority of our patients • As the therapy affects the site of pain without affecting central nervous system the patients really feel the improvement of their QoL
CONCLUSIONS • Patients want a voice in their life care, and participation in treatment, this would give them a sense of control over their disease • It is hightly depended of staff management quality