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Spectrum of Acute Coronary Syndromes. Stable Angina. Unstable Angina. Non-Q wave MI. Q wave MI. Non ST Elevation ACS. ST Elevation MI. ECG - ST. ECG - ST. CK-MB. Troponin. CRP. Cannon CP. 1999. TIMI IIIB: Troponin I vs. 42 Day Mortality.
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Spectrum of Acute Coronary Syndromes Stable Angina Unstable Angina Non-Q wave MI Q wave MI Non ST Elevation ACS ST Elevation MI ECG - ST ECG - ST CK-MB Troponin CRP Cannon CP. 1999
TIMI IIIB: Troponin I vs. 42 Day Mortality Antman et al. NEJM 1996;335: 1342-9. 7.5 8 C2 p<0.001 7 6.0 6 5 3.7 3.4 4 Death by 42 Days (%) 3 1.7 2 1.0 1 831 174 148 134 50 67 0 0-<0.4 0.4-<1.0 1.0-<2.0 2.0-<5.0 5.0-<9.0 > 9.0 cTnI at Baseline (ng/ml) Risk Ratio 1.0 1.8 3.5 3.9 6.2 7.8
P < 0.00001 TIMI 11B P = 0.0008 cTnI SUBSTUDY P = 0.005 P = 0.04 Results Baseline cTnI and Outcomes by 14 Days