I ndustrial P artnership for R esearch in I nterfacial and M aterials E ngineering

1. Industrial • Partnership for • Research in • Interfacial and • Materials • Engineering

2. IPRIME History • CIE (Center for Interfacial Engineering) • Funded by NSF from 1988 to 1999. • Industrial outreach • Ongoing industrial interest justified new organization • IPrime (Industrial Partnership for Interfacial and Materials Engineering) • Legacy organization from CIE.

3. IPRIME University-Industry partnership based on two-way knowledge exchange • Highly interdisciplinary (54 faculty in 10 departments): • Biochemistry, Molecular Biology and Biophysics • Bioproducts and Biosystems Engineering • Chemical Engineering and Materials Science • Chemistry • Physics • Mechanical Engineering • Biomedical Engineering • Electrical and Computer Engineering • Pharmaceutics • Soil, Water, and Climate • Pre-competitive and non-proprietary • 8 research programs (4 MRSEC and 4 others) • One of the largest MRSECs, Tim Lodge—Director • ~3 million per year (6 yr grant – renewed 2008)

4. Industrial Support • More than $1,500,000 per year in contributions from 40 companies. • Sponsor Membership ($50,000 per year) • Participation in up to 4 research programs • Possibility of an Industrial Fellow • Participation on the Policy and Planning Board (PPB) • Affiliate Membership ($40,000 per year) • Participation in one 1 research program, no Industrial Fellow • Small company option • $7,500 minimum • Or 0.03% of sales per year, up to $40,000

5. MCT Members

6. Denmark:Coloplast Germany:Henkel

7. Research Programs • Biocatalysis and Biosynthesis (BB) • Biomaterials and Pharmaceutical Materials (BPM) • Coating Process Fundamentals (CPF) • Magnetic Heterostructures (MH) - MRSEC • Microstructured Polymers (MP) - MRSEC • Nanoparticle Technology(NPT) - MRSEC • Nanostructural Materials and Processes (NMP) • Organic Optoelectronic Interfaces (OEI) - MRSEC www.iprime.umn.edu

8. Why IPRIME? • Partnership • Future employees • Facilities • Technology Transfer

9. Companies Scientific exchange with academic sector Influence research directions Leverage government funding (MRSEC $3M/yr) Portal/referral to other U resources/capabilities Industrial Fellows Faculty & Students Industry source of research topics Funding support Technology implementation Fosters faculty interactions Industrial Fellows Partnership

10. Industrial FellowsCurrent

11. Companies Early access to students Most work at IPRIME companies after graduation Faculty & Students Early student access to employers Learn industrial research process and interactions Hone communication skills Résumés distributed Future Employees

12. Companies CharFac (training) Imaging Center Polymer synthesis Polymer Characterization Facility (rheology) Coating Process and Visualization Lab Tissue mechanics Faculty and students In-kind equipment contributions Industrial utilization of facilities Facilities

13. IT Characterization Facility (www.charfac.umn.edu) Greg Haugstad, Director • Highlights • $15 million worth of equipment • 2 sites • 6 New Instruments • 15 Analytical Professionals • 13.85 FTE; 8 PhD, 3 masters • > 230 person years of experience • Training and certification for hands-on use • Workshops and classes • Instrument development • Users • 140 UMN faculty research groups • 20 other universities • 63 companies

14. Technology Transfer • Annual Meeting (May 26 – May 28, 2009) • Workshops • Program Reviews • Short courses (additional cost) • Coating Process Fundamentals (June 2-4, 2009) • Rheology (June 7-12, 2009) • Website with members-only features • Industrial Fellows • Special Projects (proprietary research)

15. Workshops 2009 Annual Meeting Materials for Convergent Biomedical Products – Ron Siegel, coordinator Coating Characterization: Methods & Challenges – Lorraine Francis, coordinator Sustainable Polymers – Marc Hillmyer, coordinator Flexible Organic Electronics – Dan Frisbie, coordinator Renewable Energy Materials – Uwe Kortshagen, coordinator 2009 Mid-Year Workshop(s) Polymer Adhesion (Jan. 14) CharFac Lab Demo: (Jan. 15) Particulate Coatings: Processing and Applications (Jan. 15) 2008 Annual Meeting (May 27-May 29) Materials Properties of Pharmaceuticals (BPM-Siegel) Challenges in Liquid Coating Application (CPF-Francis) Nanocomposites (MP-Hillmyer) Colloidal Nanoparticles for Printed Electronics and Photovoltaics (NPT-Kortshagen) Organic Optoelectronics for Energy Efficient Applications (OEI-Frisbie) 2008 Mid-Year Workshops Synthetic Biomaterials and Biointerfaces (Jan. 15) Materials, Devices and Coating Processes for Printed Electronics (Jan. 16)

16. www.iprime.umn.edu

17. Research Programs • Biocatalysis and Biosynthesis (BB) • Biomaterials and Pharmaceutical Materials (BPM) • Coating Process Fundamentals (CPF) • Magnetic Heterostructures (MH) - MRSEC • Microstructured Polymers (MP) - MRSEC • Nanoparticle Technology(NPT) - MRSEC • Nanostructural Materials and Processes (NMP) • Organic Optoelectronic Interfaces (OEI) - MRSEC www.iprime.umn.edu

18. Biocatalysis and Biosynthesis Program - BB InvestigatorDepartmentExpertise Michael Sadowsky* Soil,Water,ClimateEnzymes for bioremediation and bioenergy, enzyme discovery, functional and meta genomics Mark D. Distefano Chem/Med ChemOrganic and Biochem., Protein conjugates for therapeutic and biotechnology applications Romas Kazlauskas Biochem. Biocatalytic synthesis of chemical intermediates and biofuels. Enzymes modification for new reactions Claudia Schmidt-Dannert Biochem.Biosynthetic pathway engineering, metabolic engineering, gene discovery and enzyme engineering Friedrich Srienc CEMS Cell population dynamics, metabolic engineering, synthesis of polymers Lawrence P. Wackett Biochem.Microbial catabolic enzymology, functional genomics, enzyme development for bioremediation and bioenergy Ping WangBioprod/Biosys. Eng. Enzyme engineering and nanotechnology, membrane and interfacial catalysis, bioactive materials and coatings, CO2 conversion to methanol, biofuel cells, biosensors. Applications: Fine and specialty chemical production; Biofuels and biosensors; Bioremediation; Bioactive compounds; Enzyme Evolution, Biodegradable polymers and biocoatings, Pathway engineering *Program Director

19. Biomaterials and Pharmaceutical Materials - BPM InvestigatorDepartmentExpertise Ron Siegel* Pharm/BME Drug and hormone delivery, biosensing, hydrogels, microfabrication Bob Tranquillo BME/CEMS Biopolymers as tissue scaffolds; cell-matrix interactions Marc Hillmyer Chemistry Biocompatible block copolymers for polymersomes/drug delivery and worm-like micelle/tissue scaffolds Effi Kokkoli CEMS Bioadhesion and drug targeting Raj Suryanarayanan Pharm Solid state properties of drugs, stability of drug/biomaterial formulations Chun Wang* BME Biomaterial/tissue interactions, gene delivery, immunotherapy Wei Shen BME Bioactive materials • composition-structure-functional property relationships and microstructural mechanical models of native and bioartificial tissues • cell-based fabrication of bioartificial tissues • novel tissue mechanical testing and analysis methods • biomaterials for drug delivery and tissue engineering *Program Director

20. Coating Process Fundamentals—CPF Investigator Expertise Lorraine F. FrancisSolidification, stress development, microstructure, properties Marcio S. Carvalho* Fluid mechanics, rheology, numerical methods Satish Kumar Transport processes, interfacial phenomena, microfluidics Alon V. McCormick Curing, thermodynamics & kinetics, NMR, stress development H.Ted Davis Drying, porous media, cryo-microscopy, wetting and spreading Chris Macosko Rheology, polymer processing David Norris Nanomaterials, photonics, colloids Wieslaw Suszynski** Coating process experiments, apparatus, flow visualization Michael Tsapatsis Zeolite coatings, separations *Pontifica Universidade Catolica, Rio de Janeiro **Research Engineer and Laboratory Coordinator

21. Magnetic Heterostructures—MH Investigator Department Expertise Paul Crowell PHYS Magneto-optics/time-resolved studies E. Dan Dahlberg PHYS Thin film magnetism, transport, MFM Allen M. Goldman PHYS Electron tunneling/transport, MBE Christopher Leighton CEMS Magnetic films/heterostructures, transport Bethanie J. H. Stadler ECE Magneto-optical materials, thin films Randall Victora ECE Theory/modeling of magnetic materials Jianping Wang ECE Magnetic materials for recording and spintronics Renata Wentzcovitch CEMS Electronic structure calculations Develop a fundamental understanding of interfaces in magnetic heterostructures, with a focus on spin transport and dynamics

22. Synthesis, characterization, dynamics, processing, properties, and theory Microstructured Polymers - MP Investigator Department Expertise Marc A. Hillmyer CHEM Polymer synthesis and characterization (Director: Polymer Synthesis Facility) Frank S. Bates CEMS Thermodynamics, scattering, synthesis Timothy P. Lodge CHEM/CEMS Polymer dynamics, solutions, scattering Chris Macosko CEMS Rheology, processing David C. Morse CEMS Theory and modeling David Giles CEMS staff Polymer Characterization Facility Affiliated Investigators Ed Cussler (CEMS), Lorraine Francis (CEMS), Dan Frisbie (CEMS), Tom Hoye (CHEM), Efie Kokkoli (CEMS), Chris Leighton (CEMS), Ron Siegel (PHRM), Bill Tolman (CHEM)

23. Nanostructural Materials & Processes—NMP Investigator Department Expertise Alon McCormick CEMS Reaction Engineering of Materials Synthesis; Spectroscopy; Molecular Simulation H. Ted Davis CEMS Colloid and Interface Science; Statistical Mechanics C. Daniel Frisbie CEMS Molecular Materials and Interfaces; Molecular Electronics Wayne Gladfelter CHEM Materials Chemistry; Inorganic Chemistry; Scanning Probe Microscopy Greg Haugstad CHAR FAC AFM Scanning Probe Microscopy(Director, Characterization Facility) David Norris CEMS Photonic Crystals; Nanocrystals; Colloids Andreas Stein CHEM Solid State Chemistry of Porous Materials Associated Investigators: Michael Tsapatsis – Frank Bates – Lee Penn synthesis, phase behavior,structure, and performance of surfactants and self-assembled molecular and colloid systems

24. Nanoparticle Technology - NPT Investigator Department Expertise Uwe Kortshagen ME Nanoparticle synthesis, characterization Eray Aydil CEMS NP/NW materials for solar cellsStephen A. CampbellECE Micro- and nanoscale device fabrication, characterization (Dir.Nanofabrication Center) William Gerberich CEMS Micromechanical characterization nano-indentation Steven Girshick ME Particle nucleation modeling, thermal plasma CVD Joachim Heberlein ME Thermal plasma arc technology David Norris CEMS Colloidal NPs Synthesis, functionalization, characterization, integration

25. Organic Optoelectronic Interfaces - OEI Organic Optoelectronic Interfaces - OEI Investigator Department Expertise C. Daniel Frisbie CEMS Organic electronics, OFETs, AFM David Blank CHEM Ultrafast optical spectroscopy Jean-Luc Brédas CHEM (GA Tech)Computational quantum chemistry Chris Douglas CHEM Organic synthesis Russell Holmes CEMS OLEDs, Solar cells, Thin film growth Paul Ruden ECE Device modeling Xiaoyang Zhu CHEM Ultrafast photoemission spectroscopy Investigator Department Expertise C. Daniel Frisbie CEMS Organic electronics, OFETs, AFM David Blank CHEM Ultrafast optical spectroscopy Jean-Luc Brédas CHEM (GA Tech)Computational quantum chemistry Chris Douglas CHEM Organic synthesis Russell Holmes CEMS OLEDs, Solar cells, Thin film growth Paul Ruden ECE Device modeling Xiaoyang Zhu CHEM Ultrafast photoemission spectroscopy Organic synthesis, thin film growth and characterization, spectroscopy, devices, electronic structure theory & modeling

26. Characterization Facility Staff (two sites) Characterization Facility Staff (two sites) 13 ¼ FTE Technical specialists Support